Protein Alignment D and sox-2

DIOPT Version :10

• Sequence 1: NP_524066.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_741836.1
• Gene: sox-2 / 181002
• WormBaseID: WBGene00004949
• Length: 283
• Species: Caenorhabditis elegans
• Alignment Length: 331
• Identity: 108/331 - (32%)
• Similarity: 146/331 - (44%)
• Gaps: 103/331 - (31%)

  Fly    56 PNGPAGQGVNGSSGMGHHM----SSHMTPHHMHQAVSAQQTLSPNSSIGSAGSLGSQSSLGSNGS 116
            |:....|..:|.| .|.||    |:::.|..|...:|.    .|:          |..|.|.:|.
 Worm     5 PDSAKMQDYSGWS-FGFHMPPTSSTNLLPQSMPDDLSN----GPD----------SPDSTGKDGK 54

  Fly   117 GLNSSSGHQSAGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWK 181
                                ..:..:||||||||||||.||:::|.:||||||||||||||.|||
 Worm    55 --------------------KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWK 99

  Fly   182 LLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQGGLQMQAGGMGQQKLGAGPG 246
            :|:|.||||||||||||||:|||||||||||||||.|   :...:.|..:..|.:..
 Worm   100 MLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTK---SINKKNGAPIPFGNLDT-------- 153

  Fly   247 AGAGGYNPFHQLPPY-------FAPSHHLDQ--GYPVPYFGGFDPLALSKLHQSQAAAAAAVNNQ 302
                      :.|.|       .|.:.::||  ..|.|.....|.:..|..:...:...
 Worm   154 ----------KTPSYPTLTTNWNATNQYIDQFRFAPYPTTTVMDQIPFSLTYPVHSVPT------ 202

  Fly   303 GQQQGQAPPQLPPTSLSSFYSGIYSGISAPSLYAAHSANAAGLYPSSSTSSPGSSPGTITPNGMD 367
               ...:|.|..|:.:|:.::|.|                  |.|.|. |||..|..|:
 Worm   203 ---DNSSPSQFQPSPMSTNFAGSY------------------LTPKSE-SSPVGSDSTV------ 239

  Fly   368 GSMDSA 373
            |::||:
 Worm   240 GTVDSS 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_524066.1	HMG-box_SoxB	140..219	CDD:438790	63/78 (81%)
sox-2	NP_741836.1	HMG-box_SoxB	58..137	CDD:438790	64/81 (79%)