DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment D and hmg-4

DIOPT Version :9

Sequence 1:	NP_001261830.1	Gene:	D / 39570	FlyBaseID:	FBgn0000411	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_498633.1	Gene:	hmg-4 / 176052	WormBaseID:	WBGene00001974	Length:	697	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	44/230 - (19%)
Similarity:	81/230 - (35%)	Gaps:	54/230 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EDYAPQSQLQLSPGMDMDIKRVLHYSQSLAAMGGSPNGPAGQG-VNGSSGMGHHM--SSHMTPHH 82
            |||          .:|.|||:.....:|....|..|:.....| ...|||.|...  |....|..
Worm   469 EDY----------DLDKDIKKKKEDKESSEGTGSEPDDEYDSGSEQDSSGTGESEPDSEQDVPSK 523

  Fly    83 MHQAVSAQQTLSPNSSIGSAGSLGSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEGHIKRPMN 147
            ..:....::...........|..|.:..                        .|...   ||..:
Worm   524 RRKGEPKEKREKKEKREKKEGKKGKKDK------------------------DPNAP---KRATS 561

  Fly   148 AFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYR 212
            |:|.|....|.::.:|...:  ::::|:.||:||.::..:|:.:.::|:..::.:.||..:|:
Worm   562 AYMQWFLASRNELKEDGDSV--ADVAKKGGAKWKTMSSDDKKKWEEKAEEDKSRYEKEMKEYR-- 622

  Fly   213 PRRKPKNPLTAGPQGGLQMQAGGMGQQKLGAGPGA 247
                 ||    ||.......:.....:| .:||.:
Worm   623 -----KN----GPPSSSSKPSSSKTSKK-SSGPSS 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	17/70 (24%)
hmg-4	NP_498633.1	SSrecog	75..285	CDD:281523
		PH2_SSRP1-like	332..429	CDD:270051
		HMGB-UBF_HMG-box	556..619	CDD:238686	16/67 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910