Protein Alignment D and sox10

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_571950.1
• Gene: sox10 / 140616
• ZFINID: ZDB-GENE-011207-1
• Length: 485
• Species: Danio rerio
• Alignment Length: 510
• Identity: 124/510 - (24%)
• Similarity: 185/510 - (36%)
• Gaps: 192/510 - (37%)

  Fly    27 SQLQLSPGMDMDIKRVLHYSQSLAAMGGSPNG-----PA-----------GQGVNGSSGMGHHMS 75
            |::::|||:..|     .:|.|.....|:|.|     |.           |.||:|...:.....
Zfish     9 SEVEMSPGVSDD-----GHSMSPGHSSGAPGGADSPLPGQQSQMSGIGDDGAGVSGGVSVKSDEE 68

  Fly    76 SHMTPHHMHQAVSAQQTLSPNSSIGSAGSLGSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEG 140
            ....|..:.:|||  |.|:           |...:|......:||.|          .:.|
Zfish    69 DDRFPIGIREAVS--QVLN-----------GYDWTLVPMPVRVNSGS----------KSKP---- 106

  Fly   141 HIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKE 205
            |:||||||||||::..||::|...|.:||:|:||.||..|:||.|::|||||:||:|||..|.|:
Zfish   107 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNETDKRPFIEEAERLRKQHKKD 171

  Fly   206 HPDYKYRPRRK------------------------------------------------------ 216
            :|:|||:|||:
Zfish   172 YPEYKYQPRRRKNGKPGSSSEADAHSEGEVSHSQSHYKSLHLEVAHGGAAGSPLGDGHHPHATGQ 236

  Fly   217 ---PKNPLTAGPQGGLQMQAGGMGQQKLGA---GPGAGAGG------------------------ 251
               |..|.|. |:..||....|.|:::.||   |.|.||.|
Zfish   237 SHSPPTPPTT-PKTELQGGKSGEGKREGGASRSGLGVGADGSSASSSASGKPHIDFGNVDIGEIS 300

  Fly   252 ------YNPF--HQLPPYFAPSHH------LDQGYPVP--YFGGFDPLALSKLHQSQAAAAAAVN 300
                  ..||  ::...|..|:.|      ...|...|  .:|....||.:..|.:...:...:.
Zfish   301 HDVMANMEPFDVNEFDQYLPPNGHPQASATASAGSAAPSYTYGISSALAAASGHSTAWLSKQQLP 365

  Fly   301 NQ-------GQQQGQAPPQLP-------------PTSLSSFYSGI-----------YSGISAPSL 334
            :|       |:.|.::....|             |.:|..:.|..           |:...|...
Zfish   366 SQQHLGADGGKTQIKSETHFPGDTAASGSHVTYTPLTLPHYSSAFPSLASRAQFAEYAEHQASGS 430

  Fly   335 YAAHSANAAGLY-------PS-----SSTSSPGSSPGTITPNGMDGSMDSALRRP 377
            |.|||:..:|||       ||     ::...|||.|.:.:|...:..:.:.|.||
Zfish   431 YYAHSSQTSGLYSAFSYMGPSQRPLYTAIPDPGSVPQSHSPTHWEQPVYTTLSRP 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	41/70 (59%)
sox10	NP_571950.1	Sox_N	13..97	CDD:289229	22/101 (22%)
		SOX-TCF_HMG-box	107..177	CDD:238684	40/69 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810