Protein Alignment D and SOX21

DIOPT Version :10

• Sequence 1: NP_524066.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_009015.1
• Gene: SOX21 / 11166
• HGNCID: 11197
• Length: 276
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 118/274 - (43%)
• Similarity: 143/274 - (52%)
• Gaps: 64/274 - (23%)

  Fly   141 HIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKE 205
            |:||||||||||||.|||::|::||||||||||||||||||||.||||||||||||||||:||||
Human     7 HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKE 71

  Fly   206 HPDYKYRPRRKPKNPLTAG------PQGGLQMQAGGMGQQ-----KLGAGPGAGAGG-------- 251
            |||||||||||||..|...      |.|     .||:...     |.|||..|||||
Human    72 HPDYKYRPRRKPKTLLKKDKFAFPVPYG-----LGGVADAEHPALKAGAGLHAGAGGGLVPESLL 131

  Fly   252 YNPFHQLPPYFAPSHHLDQGYPVPYFGGFDPLALSKLHQSQAAAAAA--------------VNNQ 302
            .||........|.:..:           |.|       ||.||||||              :.::
Human   132 ANPEKAAAAAAAAAARV-----------FFP-------QSAAAAAAAAAAAAAGSPYSLLDLGSK 178

  Fly   303 GQQQGQAPPQLPPTSLSSF---YSGIYSGISAPSLYAAHSANAAGLYPSSSTSSPGSSPGTITPN 364
            ..:...:...||..|...:   .:|.:.|.:|.   ||.:|.|||.: :.|..||| :||.:.|.
Human   179 MAEISSSSSGLPYASSLGYPTAGAGAFHGAAAA---AAAAAAAAGGH-THSHPSPG-NPGYMIPC 238

  Fly   365 GMDGSMDSALRRPV 378
            .........|:.|:
Human   239 NCSAWPSPGLQPPL 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_524066.1	HMG-box_SoxB	140..219	CDD:438790	69/77 (90%)
SOX21	NP_009015.1	HMG-box_SoxB	6..85	CDD:438790	69/77 (90%)
		SOXp	77..>95	CDD:463537	9/17 (53%)