Protein Alignment Sox21b and SOX13

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_005677.2
• Gene: SOX13 / 9580
• HGNCID: 11192
• Length: 622
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 106/364 - (29%)
• Similarity: 154/364 - (42%)
• Gaps: 73/364 - (20%)

  Fly    14 LSLAHPLQTHLGSGGGTHHLGQ--LAAAVHQQQQQQ-----QQSDQGLGHSHHLHGQQLSLN--- 68
            |.:.|.|.| |.....|.|..|  :||.:.::||||     ||.:|.......|..||..:|
Human   153 LVMIHQLST-LRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQ 216

  Fly    69 ---HQHHHPH-QSPQHQQQHQHHPCSSNSSNGSPNGSTGLGLHPHSALHLAHHHSQLHQ------ 123
               .|.:.|: ..|.....||..|.       :|:....|.:.|.....:.:....||.
Human   217 QQIQQVNMPYVMIPAFPPSHQPLPV-------TPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVV 274

  Fly   124 --------HHPAGQQQQHSQP------------PVSSSSTSHHSQSQALSHQTHSNGSSQLGGGS 168
                    |||.   |:.|||            |.:|||.|....|......:|...:..|....
Human   275 KRPGAMATHHPL---QEPSQPLNLTAKPKAPELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSP 336

  Fly   169 AS-GAGSVAGGAANSHHSAPASSSVMAAAAAAHLHHNS-QASPISNLHQNMGSLMNSGSS----- 226
            .| ..|.:..|.|       .:.::..|....|.|..: ..||.:...:::.||.:|.:.
Human   337 PSLPLGFLGEGDA-------VTKAIQDARQLLHSHSGALDGSPNTPFRKDLISLDSSPAKERLED 394

  Fly   227 -----ASDVFFSLMIQNT---TKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLG 283
                 ..:...|..:..:   .:.:|..||||||||||||::.:||||.|..|.||||.|||.||
Human   395 GCVHPLEEAMLSCDMDGSRHFPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILG 459

  Fly   284 AEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRK 322
            :.||.:|.:||:|:.:|..||...|::::|||||:||.|
Human   460 SRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	41/70 (59%)
SOX13	NP_005677.2	SOX-TCF_HMG-box	423..494	CDD:238684	41/70 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810