Protein Alignment Sox21b and IXR1

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_012893.3
• Gene: IXR1 / 853836
• SGDID: S000001515
• Length: 597
• Species: Saccharomyces cerevisiae
• Alignment Length: 604
• Identity: 136/604 - (22%)
• Similarity: 209/604 - (34%)
• Gaps: 186/604 - (30%)

  Fly    10 SLTGLSLAHPLQTHLGSGGGTHH--LGQLAAAVHQQQQQQQQSDQGLGHSHHLHGQQLSLNHQHH 72
            ||....|.|....:..:...|.|  |.|..|...||||||||..|          ||....:|.|
Yeast    25 SLQYQGLEHNDSQYRDASHQTPHQYLNQFQAQPQQQQQQQQQQQQ----------QQQQAPYQGH 79

  Fly    73 HPHQSPQHQQQHQHHPCSSNS----------------------SNGSPNGSTGLGLHPHSALHLA 115
            . .||||.|||:.::|....|                      ||.:.|.:..:...|....::.
Yeast    80 F-QQSPQQQQQNVYYPLPPQSLTQPTSQSQQQQQQQQQQQYANSNSNSNNNVNVNALPQDFGYMQ 143

  Fly   116 HHHSQLHQHHPAGQQQQHSQPPVSSSSTSHHSQSQALSHQTHSNGSSQLGGGSASGAGSVAGGAA 180
            ...|  .|::|...|||.|:  ..:|..||.:|.|.....|.:..||    .:.|...:|:.| .
Yeast   144 QTGS--GQNYPTINQQQFSE--FYNSFLSHLTQKQTNPSVTGTGASS----NNNSNNNNVSSG-N 199

  Fly   181 NSHHSAPAS------SSVMAAAAAAHLHHNSQASPISNLHQ----------NMGSL------MNS 223
            ||..|.||.      :...||||||    |:.|.|.|.|.|          ||.:|      .::
Yeast   200 NSTSSNPAQLAASQLNPATAAAAAA----NNAAGPASYLSQLPQVQRYYPNNMNALSSLLDPSSA 260

  Fly   224 GSSASDVFFS------------------------LMIQNTTKRQNEEHI---------------- 248
            |::|.:...:                        |.:|...:.|.::.:
Yeast   261 GNAAGNANTATHPGLLPPNLQPQLTHHQQQMQQQLQLQQQQQLQQQQQLQQQHQLQQQQQLQQQH 325

  Fly   249 ------------------------------------KRPMNAFMVWSRLQRRKIAQDNPKMHNSE 277
                                                |||.:|:.::|...|.::.|..|:....|
Yeast   326 HHLQQQQQQQQHPVVKKLSSTQSRIERRKQLKKQGPKRPSSAYFLFSMSIRNELLQQFPEAKVPE 390

  Fly   278 ISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALRRDGYPYPMP--YPSV 340
            :||...|.||.||:::|:||.:|                :|...:...:.||.|...:|  .||.
Yeast   391 LSKLASARWKELTDDQKKPFYEE----------------FRTNWEKYRVVRDAYEKTLPPKRPSG 439

  Fly   341 PVEALRAGITPGYFAPGPTAAAYHLGSHLGQ--TSTPTTTQATLSGQMDKFALE-RSSYLSNSSQ 402
            |.......|.|......|......:...:|:  .......:|..:....|...| .|.|...:..
Yeast   440 PFIQFTQEIRPTVVKENPDKGLIEITKIIGERWRELDPAKKAEYTETYKKRLKEWESCYPDENDP 504

  Fly   403 ASAYSAYLDPSVLTKAYFDSKMYQDR------AANYAFDISKIYGAQQHAA----------AHHQ 451
            ....:.:...::......|:|:.:::      .||   .|..:.|:..::.          :..|
Yeast   505 NGNPTGHSHKAMNMNLNMDTKIMENQDSIEHITAN---AIDSVTGSNSNSTNPNTPVSPPISLQQ 566

  Fly   452 QQQQQQQQQQQQQQQLLLS 470
            |..|||||||||||.:||:
Yeast   567 QPLQQQQQQQQQQQHMLLA 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	21/130 (16%)
IXR1	NP_012893.3	NHP6B	<338..501	CDD:227935	37/178 (21%)