Protein Alignment Sox21b and SOX7

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_113627.1
• Gene: SOX7 / 83595
• HGNCID: 18196
• Length: 388
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 85/327 - (25%)
• Similarity: 121/327 - (37%)
• Gaps: 160/327 - (48%)

  Fly   244 NEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMH 308
            :|..|:|||||||||::.:|:::|..||.:||:|:||.||..||.||..:|||::|||:|||..|
Human    41 SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQH 105

  Fly   309 MKEHPDYKYRPRRKPKALRR--------------------------------------------- 328
            |:::|:||||||||.:|.|.
Human   106 MQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTA 170

  Fly   329 ------------------------DGYPYPMPYP------------------------------- 338
                                    |.|||.:|.|
Human   171 LPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIP 235

  Fly   339 ------------------SVPVEALRAGITPG---------------YFAPGPTAAAYH-----L 365
                              |.|:.:|..|.:||               |::|    |.||     |
Human   236 HLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSP----ATYHPLHSNL 296

  Fly   366 GSHLGQTSTP----------TTTQATLSGQMDKFALERSSYLS------NSSQASAYSAYLDPSV 414
            .:||||.|.|          ..:|..|.|.||:  .|...||:      :::.|.|.|.::..|.
Human   297 QAHLGQLSPPPEHPGFDALDQLSQVELLGDMDR--NEFDQYLNTPGHPDSATGAMALSGHVPVSQ 359

  Fly   415 LT 416
            :|
Human   360 VT 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	45/78 (58%)
SOX7	NP_113627.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..46		1/4 (25%)
		HMG-box_SoxF_SOX7	34..121	CDD:438849	46/79 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..197		1/56 (2%)
		Sox17_18_mid	<198..230	CDD:463454	4/31 (13%)