Protein Alignment Sox21b and sox18

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_017209261.1
• Gene: sox18 / 797246
• ZFINID: ZDB-GENE-080725-1
• Length: 431
• Species: Danio rerio
• Alignment Length: 436
• Identity: 117/436 - (26%)
• Similarity: 160/436 - (36%)
• Gaps: 127/436 - (29%)

  Fly   138 VSSSSTSHHSQSQALSHQTHSNGSSQLGGGSASGAGSVAGGAANSH--------HSAPASSS--- 191
            :|.||....:.||          .||:......||.|...|....|        ..||...|
Zfish     3 ISESSCCQEASSQ----------PSQVAERGTWGASSSTPGPERGHGFDRSRTTELAPVPGSGTR 57

  Fly   192 -VMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTKRQNEEHIKRPMNAF 255
             |...||.|.........|        |:| ..|||..            |...|..|:||||||
Zfish    58 TVSRTAAEARTGSPDSTRP--------GAL-TLGSSEG------------KSGGESRIRRPMNAF 101

  Fly   256 MVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPR 320
            |||::.:|:::|..||.:||:.:||.||..||.|:..:||||::||:|||..|:::||:||||||
Zfish   102 MVWAKDERKRLAIQNPDLHNAVLSKMLGQSWKALSTLDKRPFVEEAERLRLQHLQDHPNYKYRPR 166

  Fly   321 RK--PKALRRDGYPYPMPYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQ------TSTPTT 377
            ||  ||.::|       ..|.:.::.|..| .|| .|..|...|:||...||.      :..|
Zfish   167 RKKQPKKMKR-------VEPGLLLQGLAHG-GPG-DAYSPHRHAHHLLPPLGHFRDLHPSGAP-- 220

  Fly   378 TQATLSGQMDKFAL--ERSSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAANYAFDISKIY 440
                   :::.|.|  ...|.|....:....|.:..|.:.......|.:      ||       :
Zfish   221 -------ELESFGLPTPEMSPLDVLEEGGGDSVFFPPHMQEDVGLSSWI------NY-------H 265

  Fly   441 GAQQHAAAHHQQQQQQQQQQQQQQQQLLLSGGGGSGGGGSASSHNN-NSSSGLDDRDATPQLEAV 504
            ....|...||........|.                      ||.: |..|.|.......:...|
Zfish   266 QHPNHQPGHHPHHNSHNLQH----------------------SHPHLNQKSPLACLPLQEKCLVV 308

  Fly   505 ESK------PHLHSPSDVGLDYAQYAQQYG------------GQLA 532
            ||.      |::..|......|  |.|.||            |||:
Zfish   309 ESPNPGGLYPNMTLPESSKAGY--YGQIYGSSQPQPAFTSHLGQLS 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	37/70 (53%)
sox18	XP_017209261.1	SOX-TCF_HMG-box	93..164	CDD:238684	37/70 (53%)
		Sox_C_TAD	207..429	CDD:288887	34/192 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940