| Sequence 1: | NP_001261829.1 | Gene: | Sox21b / 39569 | FlyBaseID: | FBgn0042630 | Length: | 587 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003131.1 | Gene: | SRY / 6736 | HGNCID: | 11311 | Length: | 204 | Species: | Homo sapiens |
| Alignment Length: | 139 | Identity: | 62/139 - (44%) |
|---|---|---|---|
| Similarity: | 93/139 - (66%) | Gaps: | 6/139 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 195 AAAAAHLHHNSQASPISNLHQNMGSLMNSGS----SASDVFFSLMIQNTTKRQNEEHIKRPMNAF 255
Fly 256 MVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPR 320
Fly 321 RKPKALRRD 329 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sox21b | NP_001261829.1 | HMG-box_SoxB | 246..325 | CDD:438790 | 51/78 (65%) |
| SRY | NP_003131.1 | HMG-box_SoxA_SRY | 56..140 | CDD:438843 | 53/83 (64%) |
| Sufficient for interaction with KPNB1. /evidence=ECO:0000269|PubMed:15297880 | 59..136 | 51/76 (67%) | |||
| Required for nuclear localization. /evidence=ECO:0000269|PubMed:12764225, ECO:0000269|PubMed:15746192 | 61..77 | 13/15 (87%) | |||
| Sufficient for interaction with EP300. /evidence=ECO:0000269|PubMed:15297880 | 107..139 | 18/31 (58%) | |||
| Required for nuclear localization. /evidence=ECO:0000269|PubMed:15297880 | 130..136 | 5/5 (100%) | |||
| Necessary for interaction with ZNF208 isoform KRAB-O. /evidence=ECO:0000269|PubMed:15469996 | 138..155 | 1/4 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 175..204 | ||||
| Necessary for interaction with SLC9A3R2. /evidence=ECO:0000269|PubMed:9054412 | 198..204 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||