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Protein Alignment Sox21b and SOX12

DIOPT Version :9

Sequence 1:	NP_001261829.1	Gene:	Sox21b / 39569	FlyBaseID:	FBgn0042630	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_008874.2	Gene:	SOX12 / 6666	HGNCID:	11198	Length:	315	Species:	Homo sapiens

Alignment Length:	301	Identity:	93/301 - (30%)
Similarity:	127/301 - (42%)	Gaps:	76/301 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 HIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKE 311
            |||||||||||||:.:||||....|.|||:|||||||..|:||.:.||.||:.||:|||..||.:
Human    39 HIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMAD 103

  Fly   312 HPDYKYRPRRKPKALRRDGYPYP----------MPYPSVPVEALRAGITPGYFAPGPT---AAAY 363
            :||||||||:|.|.......|.|          .|.|.:|....|..      |.||.   |||.
Human   104 YPDYKYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRA------AGGPLGGGAAAP 162

  Fly   364 H----------LGSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKA 418
            .          |...|.:|......:...:|:..:...||:...|....|:|.:|...||
Human   163 EDDDEDDDEELLEVRLVETPGRELWRMVPAGRAARGQAERAQGPSGEGAAAAAAASPTPS----- 222

  Fly   419 YFDSKMYQDRAANYAFDISKIYGAQQHAAAHHQQQQQQQQQQQQQQQQLLLSGGGGSGGGGSASS 483
                   :|.                    ..::::::....::.:::.:.||....|    ..|
Human   223 -------EDE--------------------EPEEEEEEAAAAEEGEEETVASGEESLG----FLS 256

  Fly   484 HNNNSSSGLD----DRDATPQLEAVESKPHLHSPSDVGLDY 520
            ......:|||    |||  |.|:......|...|     ||
Human   257 RLPPGPAGLDCSALDRD--PDLQPPSGTSHFEFP-----DY 290

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.