Protein Alignment Sox21b and SOX4

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_003098.1
• Gene: SOX4 / 6659
• HGNCID: 11200
• Length: 474
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 117/419 - (27%)
• Similarity: 148/419 - (35%)
• Gaps: 195/419 - (46%)

  Fly   155 QTHS--NGSSQLGGGSA-SGAGSVAGGAANSHHSAPASSSVMAAAAAAHLHHNSQASPISNLHQN 216
            ||::  |..:.|.|.|: ||||...|.|                         |..:|
Human     4 QTNNAENTEALLAGESSDSGAGLELGIA-------------------------SSPTP------- 36

  Fly   217 MGSLMNSGSSASDVFFSLMIQNTTKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKR 281
             ||..::|..|.|..:.        :....|||||||||||||:::||||.:.:|.|||:|||||
Human    37 -GSTASTGGKADDPSWC--------KTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKR 92

  Fly   282 LGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALRRDGYPYPMPYPSVPVEALR 346
            ||..||||.:.:|.|||.||:|||..||.::||||||||:|.|
Human    93 LGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVK---------------------- 135

  Fly   347 AGITPGYFAPGPTAAAYHLGSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLD 411
                                                ||.            :|||.::|.|
Human   136 ------------------------------------SGN------------ANSSSSAAAS---- 148

  Fly   412 PSVLTKAYFDSKMYQDRAANYAFDISKIYGAQQHAAAHHQQQQQQQQQQQQQQQQLLLSGGGGSG 476
                      ||..:..        .|:.|                            |||||.|
Human   149 ----------SKPGEKG--------DKVGG----------------------------SGGGGHG 167

  Fly   477 GGGSASSHN-----NNSSSGLDDRDATPQLEAVESKPHLHSPSDVGLDYAQYAQQYGGQLAAAAG 536
            |||...|.|     ..:|.|           ...|||            || .:..|.::|..||
Human   168 GGGGGGSSNAGGGGGGASGG-----------GANSKP------------AQ-KKSCGSKVAGGAG 208

  Fly   537 GAVGGGAAG--AAGGSAGGGSGGATAADF 563
            |.|....|.  .|||..||.:..|.||.|
Human   209 GGVSKPHAKLILAGGGGGGKAAAAAAASF 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	47/70 (67%)
SOX4	NP_003098.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		19/94 (20%)
		SOX-TCF_HMG-box	58..129	CDD:238684	47/70 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..228		46/243 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..286
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	302..416

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.860