Protein Alignment Sox21b and sox9a

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_571718.1
• Gene: sox9a / 60641
• ZFINID: ZDB-GENE-001103-1
• Length: 462
• Species: Danio rerio
• Alignment Length: 491
• Identity: 129/491 - (26%)
• Similarity: 204/491 - (41%)
• Gaps: 113/491 - (23%)

  Fly   148 QSQALSHQTHSNGSSQLGGG---SASGAGSVAGGAANSHHSAPASSSVMAAAAAAHLHHNSQASP 209
            |.:.||.....:.|....|.   ||||        :::.::.||.:|::||..........:...
Zfish    14 QEKCLSDAPSPSMSEDSAGSPCPSASG--------SDTENTRPAENSLLAADGTLGDFKKDEEDK 70

  Fly   210 ISNLHQNMGSLMNSGSSASDVFFSLMIQNTTKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMH 274
            .....:...|.:..|...:.|...:.:..::|  |:.|:||||||||||::..|||:|...|.:|
Zfish    71 FPVCIREAVSQVLKGYDWTLVPMPVRVNGSSK--NKPHVKRPMNAFMVWAQAARRKLADQYPHLH 133

  Fly   275 NSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALR------RDGYPY 333
            |:|:||.||..|:||.|.|||||::||:|||..|.|:||||||:|||: |:::      .||...
Zfish   134 NAELSKTLGKLWRLLNEVEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KSVKNGQSESEDGSEQ 197

  Fly   334 PMPYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQTSTPTTTQA-TLSGQMDKFALER---- 393
            ....|:...:||:...:|........:.:.|.|...|..:.|||.:. |..|:.|   |:|
Zfish   198 THISPNAIFKALQQADSPASSMGEVHSPSEHSGQSQGPPTPPTTPKTDTQPGKAD---LKREARP 259

  Fly   394 ---------------------SSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAANYAFDIS 437
                                 ||.:..:...:.:..||.|:....|.:        |..||..::
Zfish   260 LQENTGRPLSINFQDVDIGELSSDVIETFDVNEFDQYLPPNGHQNAPY--------AGGYAAWMT 316

  Fly   438 KIYGAQQHAAAHHQQ-------QQQQQQQQQQQQQQLLLSGGGGSGGGGSASSHNNNSSSGLDDR 495
            |    .|:.:....|       :..|.:....:.:||             :.||.|       ::
Zfish   317 K----PQNGSPQSSQLTPLNPAEPDQPRTTHIKTEQL-------------SPSHYN-------EQ 357

  Fly   496 DATPQLEAVES--KPHL--HSPSDVGLDYAQYAQQYGGQLAAAAGGAVGGGAAG----AAGGSAG 552
            ..:||..:..|  ..||  :|.|...:..|||......|          |||:.    |.|.|:|
Zfish   358 QGSPQHISYGSFNVQHLQHYSTSFPSITRAQYDYSDSHQ----------GGASSYYTHAGGQSSG 412

  Fly   553 GGSGGATAADFRRPL-------TVIFXPPSSNGSEE 581
            ..|..:..:..:||:       |.:. .|.||.|.:
Zfish   413 LYSTFSYMSSSQRPMYTPIADSTGVPSIPQSNHSPQ 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	48/78 (62%)
sox9a	NP_571718.1	Sox_N	22..96	CDD:463586	14/81 (17%)
		HMG-box_SoxE	106..180	CDD:438840	46/73 (63%)