Protein Alignment Sox21b and sox5

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_021330769.1
• Gene: sox5 / 567413
• ZFINID: ZDB-GENE-000607-13
• Length: 763
• Species: Danio rerio
• Alignment Length: 520
• Identity: 130/520 - (25%)
• Similarity: 192/520 - (36%)
• Gaps: 165/520 - (31%)

  Fly    13 GLSLAHPLQ----THLGSGGGTHHLGQLAAAVHQQQQQQQQSDQGLGHSHHLHGQQLSLNHQHHH 73
            |.|..:|||    |...:...|..||.|         |.||          |:..||:
Zfish   305 GCSEPYPLQLIPTTMAAAAAATPGLGPL---------QLQQ----------LYAAQLA------- 343

  Fly    74 PHQSPQHQQQHQHHPCSSNSSNGSPNGSTGLGLHPHSALHLAHHHSQLHQHHPAGQQQQHSQPPV 138
                     ..|..|.:.:|:....|.:||. |.|.|.      .|:.::..|..:.:.....|:
Zfish   344 ---------AMQVSPGAKHSTVPQANLATGT-LSPTSG------QSEKNRSTPPPKPKDEGAQPL 392

  Fly   139 SSSSTSHHSQSQALSHQTHSNGSSQ-----LGGGSAS-GAGSVAGGAANSHHSAPASSSVMAA-- 195
            :.||....|:|::.:    |..|.|     ||.||.. .|.|..||..:...|....||:.:|
Zfish   393 NLSSKPKASESKSPT----SPASPQVPALKLGPGSLKHSAPSSIGGPPSRLSSIDLLSSITSAGY 453

  Fly   196 --------------------------------AAAAHLHHNS---------QASPISNLHQNM-- 217
                                            ||...|..|:         :.:.:.:|.|.:
Zfish   454 LNDHEAVTKAFQEARKMKEQLKREEQVLDAKVAAVNSLSLNNGRSEKVRFMEKAALESLSQQLKQ 518

  Fly   218 -------GSLMNSG-SSASD----VFFSLMIQNTTKR-QNEEHIKRPMNAFMVWSRLQRRKIAQD 269
                   .::|:.| |..||    |..|.:.:....| .:|.||||||||||||::.:||||.|.
Zfish   519 SEESKFTHAMMDFGISGDSDGSPSVSDSRIFREARGRGSSEPHIKRPMNAFMVWAKDERRKILQA 583

  Fly   270 NPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKP----------- 323
            .|.||||.|||.||:.||.:|..||:|:.:|..||...|::::|||||:||.|.
Zfish   584 FPDMHNSNISKILGSRWKSMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRI 648

  Fly   324 ---KALRRD-----------GYPYPMPYPSVPVEALRAGITPGYFA----PGPTAAAYHLGSHLG 370
               ||:.|:           |....:|..|..|      :.||..:    |.|...:.|......
Zfish   649 GEYKAIMRNRRQEMRQYFTVGQQAQLPLSSAGV------VYPGALSMAGMPSPQMPSEHSSMSSS 707

  Fly   371 QTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAANYAFD 435
            ....|.|:||:...:::....|.......:..|                :|...|:|...:|..|
Zfish   708 PEPVPPTSQASYFKEVEPRVKEELRMDDGNGDA----------------YDDFDYEDDDGDYGSD 756

  Fly   436  435
            Zfish   757  756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	41/70 (59%)
sox5	XP_021330769.1	SSL_OB	332..>415	CDD:332684	26/128 (20%)
		SOX-TCF_HMG-box	561..632	CDD:238684	41/70 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910