Protein Alignment Sox21b and sox6

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001116481.1
• Gene: sox6 / 567154
• ZFINID: ZDB-GENE-081120-6
• Length: 768
• Species: Danio rerio
• Alignment Length: 548
• Identity: 128/548 - (23%)
• Similarity: 187/548 - (34%)
• Gaps: 155/548 - (28%)

  Fly    14 LSLAHPLQTHLGSGGGTHHLGQLAAAVHQQQQQQQQSDQGLGHSHHLHGQQLSLNHQHHHPHQSP 78
            |..||..|..|.:........|:..|..||:|..:|..|.|...|.::..|..:..|.|.|   |
Zfish   207 LLAAHDEQKKLAASQMEKQRQQMELARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMP---P 268

  Fly    79 ------QHQQQ----------------------HQHHPCSSNSSNGSPNGSTGLGLHPHSALHLA 115
                  .|.|:                      ..::|.....|..:...::||.......|:.|
Zfish   269 LMIPIFPHDQRTLAAAAAAQQGFLFPPGMSYKPGDNYPVQFIPSTMAAAAASGLNPLQLQQLYAA 333

  Fly   116 HHHSQLHQHHPAGQQQQHSQPP-----VSSSSTSHHSQSQALSHQTHSNGSSQLG---------- 165
            ...|.  |..|..:.....|||     :|.|...:..:|.....|....|:..|.
Zfish   334 QLASM--QVSPGAKMPPLPQPPNSAGQISPSGLKNEKRSSTPLAQVKEEGTQPLNLSARPKTAEP 396

  Fly   166 ------------GGSASGAGSVA---------GG-----------AANSHHSAPASSSVMAAAAA 198
                        .||.|...|::         ||           :.||........:||.|...
Zfish   397 IKSPTSPTQSLFPGSKSSPNSLSKSGDIPSPIGGLGRGSSLDILSSLNSTALFGDQDAVMKAIQE 461

  Fly   199 A----------HLHHNSQA----------------------SPISNLHQNMGSLMNSG------- 224
            |          .|.|:.|.                      |...||..::..|...|
Zfish   462 ARKMREQIQREQLQHHQQGMEVKLSALTSMGLNNCRTEKERSHYDNLGHHLSKLGEDGKIGHRVI 526

  Fly   225 ---------SSASDVFFSLMIQNTTKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISK 280
                     ..||.....:..:...:..||.||||||||||||::.:||||.|..|.||||.|||
Zfish   527 DLTRPEDFEGGASTTEARVYREPRGRNSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISK 591

  Fly   281 RLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRK------PKALRRDGYPYPM---- 335
            .||:.||.:|.:||:|:.:|..||..:|::::|:|||:||.|      .|.||...|...|
Zfish   592 ILGSRWKSMTNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIIDGKKLRISEYKQMMRSRR 656

  Fly   336 ------------PYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQTST---PT--TTQATLS 383
                        |...:|:......:.||......|..:.|:.|.....|.   ||  ..|:|.:
Zfish   657 QEMRQFFTVGQQPQTQIPITTSAGVVYPGAITMATTTPSPHMTSDCSSASASPEPTIPVIQSTFN 721

  Fly   384 GQMDKFALERSSYLSNSSQASAYSAYLD 411
            .:|:...:..|..::...:...|..:.|
Zfish   722 MKMEPGTMVPSDAVNGEDEMDMYEDFED 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	40/70 (57%)
sox6	NP_001116481.1	SOX-TCF_HMG-box	558..629	CDD:238684	40/70 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910