Protein Alignment Sox21b and sox9

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001016853.1
• Gene: sox9 / 549607
• XenbaseID: XB-GENE-1034769
• Length: 482
• Species: Xenopus tropicalis
• Alignment Length: 323
• Identity: 103/323 - (31%)
• Similarity: 148/323 - (45%)
• Gaps: 60/323 - (18%)

  Fly   243 QNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAM 307
            :::.|:||||||||||::..|||:|...|.:||:|:||.||..|:||.|.|||||::||:|||..
 Frog   100 KSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRIQ 164

  Fly   308 HMKEHPDYKYRPRRKP-----KALRRDGYPYPMPYPSVPVEALRAGITPGYFAPGPTAAA----- 362
            |.|:||||||:|||:.     ::.:.||.......|:...:||:        |..|.:|:
 Frog   165 HKKDHPDYKYQPRRRKSVKNGQSEQEDGAEQTHISPNAIFKALQ--------ADSPHSASSMSEV 221

  Fly   363 YHLGSHLGQTS---TPTTTQATLSGQMDKFALERSSY-LSNSSQASAYSAYLDPS--------VL 415
            :..|.|.||:.   ||.||..| ..|..|..|:|... |..|.:...:..:.|..        :.
 Frog   222 HSPGEHSGQSQGPPTPPTTPKT-DVQPGKPDLKREGRPLQESGRQPPHIDFRDVDIGELSSEVIS 285

  Fly   416 TKAYFDSKMYQ------------DRAANY--AFDISKIYGAQQHAAAHHQQQQQQQQQQQQQQQQ 466
            |...||...:.            ...|.|  ::.|:....|...|......:||||||||.|..|
 Frog   286 TIETFDVNEFDQYLPPNGHPGVGSTQAPYTGSYGINSTPSATPGAGPAWMSKQQQQQQQQPQPPQ 350

  Fly   467 LLLSGGGGSGGGGSASSHNNNSSSGLDDRDATPQLEA--VESKPHLHSPSDVGLDYAQYAQQY 527
            ..||           :.::..|.|.......|.||..  ...:...|||..  |:|:.:..|:
 Frog   351 HSLS-----------TINSEQSQSQQRTHIKTEQLSPSHYSDQQQQHSPQQ--LNYSSFNLQH 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	48/83 (58%)
sox9	NP_001016853.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..66
		Sox_N	22..94	CDD:463586
		Dimerization (DIM). /evidence=ECO:0000250|UniProtKB:P48436	63..103		0/2 (0%)
		PQA. /evidence=ECO:0000250|UniProtKB:P48436	63..103		0/2 (0%)
		HMG-box_SoxE	104..178	CDD:438840	46/73 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	160..274		37/122 (30%)
		Transactivation domain (TAM). /evidence=ECO:0000250|UniProtKB:P48436	224..308		19/84 (23%)
		9aaTAD 1. /evidence=ECO:0000250|UniProtKB:P48436	276..285		0/8 (0%)
		9aaTAD 2. /evidence=ECO:0000250|UniProtKB:P48436	291..299		1/7 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..395		27/112 (24%)
		Transactivation domain (TAC). /evidence=ECO:0000250|UniProtKB:P48436	366..482		9/37 (24%)
		9aaTAD 3. /evidence=ECO:0000250|UniProtKB:P48436	433..441
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..482