Protein Alignment Sox21b and cic

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001262755.1
• Gene: cic / 53560
• FlyBaseID: FBgn0262582
• Length: 2150
• Species: Drosophila melanogaster
• Alignment Length: 785
• Identity: 160/785 - (20%)
• Similarity: 233/785 - (29%)
• Gaps: 281/785 - (35%)

  Fly    24 LGSGGGTHHLGQLAA--AVHQQQQQQQQSDQGLGHSHHLHGQQLSLNHQHHHPHQSP-------- 78
            :||...||.....||  .|..|....|.:...| ..|....||..|..|||| ||.|
  Fly   861 VGSNSNTHVAATAAATSTVGAQPLPPQTTPVSL-VMHAPPPQQQPLQQQHHH-HQPPPPPPASLP 923

  Fly    79 -------------------------------QHQQQHQH----------------HPCSSNSSNG 96
                                           |||||.||                ||...:::..
  Fly   924 APSAPPTSGSSSSHNSVGHATSVIRISSSQQQHQQQQQHQQQAHPHVVVSGGQTFHPVIVDATQL 988

  Fly    97 S------------PNGSTGLG-----------------------LHPHSA--------------- 111
            |            ||..|...                       |.||..
  Fly   989 SVPLPPTTVSFHQPNTPTSTAASVASMSQDKMLAKNGYNAPWFKLLPHMTPMSKASPAPVTPTLT 1053

  Fly   112 ----------LHLAHHHSQLHQHHPAGQQQQHSQPPVSSSSTSHHSQSQALSHQTHSNGS----- 161
                      :.....|.||.|.....||||  .||  ....:|::....:|....|.|.
  Fly  1054 TSASSYNVVMMQQQQQHQQLQQQQQLQQQQQ--SPP--QMPLNHNNNHLIVSAPLSSPGKPLNCS 1114

  Fly   162 -SQLGGGSASGAGSVAGGAANSHHSAP----------------ASSSVMAAAAAAHLHHNSQASP 209
             :.....:|:.|.:||..........|                :::|....||.....|||....
  Fly  1115 MNDAKVAAAAAAAAVANQRQKQQQEEPDDQLDDDVFETTTPGISANSKKQTAAMRLPTHNSNIRK 1179

  Fly   210 ISNLHQN--MGSLMNSGSSASDVFFSLMIQNTTKRQN------------EEHIKRPMNAFMVWSR 260
            :...|.:  .|:...|.:.......|.:.|...::|.            .:.|:|||||||::|:
  Fly  1180 LEECHDDGAAGAPATSAAKRRSQSLSALQQQQQQQQQAGAAGTAAGQPANKKIRRPMNAFMIFSK 1244

  Fly   261 LQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKY--RPRRKP 323
            ..|:.:.:.:|...|..:||.||..|..|..|:|..:.:.|..::..|.|.||::|:  :.|||.
  Fly  1245 KHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSKDRRKS 1309

  Fly   324 KALRRDGYPYPMPYPSVPVEALRAGITPGYFAPGPTA---AAYHLGSHLGQTS-----TPTTT-- 378
            ..                     :..|||..|.|...   |...|.|..|..|     .|:|.
  Fly  1310 ST---------------------STATPGGKASGAAGTGDAKQRLVSVDGSDSLEHDMCPSTPGG 1353

  Fly   379 QATLSG-------QMDKFALERSSYLSNSSQASAYSAYLDPSVLT-KAYFDSKMYQDRAANYAFD 435
            ..:..|       |.|...|...:|.|...:|        |:.:: |...:.|:.::...:..
  Fly  1354 SGSCGGQGISSDLQGDIIPLTIDNYNSTCDEA--------PTTISMKGNGNGKLMKNELPSDE-- 1408

  Fly   436 ISKIYGAQQHAAAHHQQQQQ-----------------------QQQQQQQQQQQLLLSGGGGSGG 477
                  .:|......:||||                       ..::||.:..|........||.
  Fly  1409 ------DEQMLVVEEEQQQQTVKKIDLHCRERVNDSDMDDTPFDYRKQQPEANQRSAEEHSTSGA 1467

  Fly   478 GGSASSHNNNSSSGLDDRDATPQLEAVESKPHLHS---PSDVGLDYAQYA-----------QQYG 528
            .|.|.  |....|| .:|:.|.:.:|:::.|.|.|   |......|.||.           |..|
  Fly  1468 NGQAI--NAPPLSG-GEREITLKPKAIKAHPVLESNMLPYTQMSIYTQYTSPKNPIGVTPFQPTG 1529

  Fly   529 GQLAAAAGGAVGGGAAGAAGGS-------------------AGGGSGGATAADFRRPLTVIFXPP 574
            |...:......|.|......||                   ...|||.|:...      |:..||
  Fly  1530 GAFKSMPISPKGSGGKPEDAGSLQAHIKQEDIKQEPPSPYKLNNGSGSASGGG------VVSAPP 1588

  Fly   575 SSNGS 579
            .::||
  Fly  1589 PNSGS 1593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	29/80 (36%)
cic	NP_001262755.1	DUF4819	349..432	CDD:465014
		HMG-box_CIC-like	1231..1308	CDD:438806	27/76 (36%)