Protein Alignment Sox21b and Sox2

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001102651.1
• Gene: Sox2 / 499593
• RGDID: 1565646
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 416
• Identity: 134/416 - (32%)
• Similarity: 164/416 - (39%)
• Gaps: 155/416 - (37%)

  Fly   165 GGGSASGAGSVAGGAANSHHSAPASSSVMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASD 229
            |...|||.|   ||..|              |.||....|.:.||
  Rat    13 GPQQASGGG---GGGGN--------------ATAAATGGNQKNSP-------------------- 40

  Fly   230 VFFSLMIQNTTKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEK 294
                            :.:||||||||||||.||||:||:||||||||||||||||||||:|.||
  Rat    41 ----------------DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEK 89

  Fly   295 RPFIDEAKRLRAMHMKEHPDYKYRPRRKPKAL-RRDGYPYPMPYPSVPVEALRAGITPGYFAPG- 357
            ||||||||||||:|||||||||||||||.|.| ::|.|..|                .|..|||
  Rat    90 RPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP----------------GGLLAPGG 138

  Fly   358 -PTAAAYHLGSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFD 421
             ..|:...:|:.||         |.::.:||.:|     :::..|..| ||
  Rat   139 NSMASGVGVGAGLG---------AGVNQRMDSYA-----HMNGWSNGS-YS-------------- 174

  Fly   422 SKMYQDRAANYAFDISKIY----GAQQHAAAH----HQQQQQQQQQQQQQQQQLLLSG------- 471
              |.|::..         |    |...|.||.    |:......|.......|..::|
  Rat   175 --MMQEQLG---------YPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMS 228

  Fly   472 -------GGGSGGGGS--------------ASSHNNNSSSGLDDRDATPQLEAVESKPHLHSPSD 515
                   |...|..||              :|||:.......|.||...........|...:||.
  Rat   229 YSQQGTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSR 293

  Fly   516 VGLDYAQYAQQYGGQLAAAAGGAVGG 541
            :.:     ||.|  |.....|.|:.|
  Rat   294 LHM-----AQHY--QSGPVPGTAING 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	62/70 (89%)
Sox2	NP_001102651.1	SOX-TCF_HMG-box	42..113	CDD:238684	62/70 (89%)
		SOXp	112..202	CDD:403523	35/145 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.870