Protein Alignment Sox21b and sox3

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001007502.1
• Gene: sox3 / 493228
• XenbaseID: XB-GENE-484815
• Length: 307
• Species: Xenopus tropicalis
• Alignment Length: 345
• Identity: 113/345 - (32%)
• Similarity: 159/345 - (46%)
• Gaps: 104/345 - (30%)

  Fly   244 NEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMH 308
            ::|.:||||||||||||.||||:||:|||||||||||||||:||||::.||||||||||||||:|
 Frog    36 DQERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSDSEKRPFIDEAKRLRAVH 100

  Fly   309 MKEHPDYKYRPRRKPKA-LRRDGYPYPMPYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQT 372
            |||:||||||||||.|. |::|.|       |:|...|..|::       |.|::..:|..:
 Frog   101 MKEYPDYKYRPRRKTKTLLKKDKY-------SLPGNLLAPGVS-------PVASSVGVGQRI--- 148

  Fly   373 STPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAANYAFDIS 437
                .|.|.::|..:                .|||                :.||:
 Frog   149 ----DTYAHMNGWTN----------------GAYS----------------LMQDQ--------- 168

  Fly   438 KIYGAQQHAAAHHQQQQQQQQQQQQQQQQLLLSGGGG---SGGGGSASSHNNNSSSGLDDRDATP 499
              .|..||...:..|.||.|.:...          ||   |....||.::.|.::|
 Frog   169 --LGYSQHPGMNSPQMQQIQHRYDM----------GGLQYSPMMSSAQTYMNAAAS--------- 212

  Fly   500 QLEAVESKPHLHSPSDVGLDYAQYAQQYGGQLAAAAGGAVGGGAAGAAGGSAGGGSGGATAADFR 564
                    .:..||:        |.||....::..:.|:|......:...:....:..|...|.|
 Frog   213 --------TYSMSPA--------YNQQSSTVMSLGSMGSVVKSEPSSPPPAITSHTQRACLGDLR 261

  Fly   565 RPLTVIFXPPSSNGSEELNL 584
            ..:: :: ||..:.|:..:|
 Frog   262 DMIS-MYLPPGGDASDPSSL 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	66/78 (85%)
sox3	NP_001007502.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		1/4 (25%)
		HMG-box_SoxB	38..113	CDD:438790	63/74 (85%)
		SOXp	109..189	CDD:463537	32/143 (22%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	259..270		2/11 (18%)