Protein Alignment Sox21b and sox2

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_998869.1
• Gene: sox2 / 407873
• XenbaseID: XB-GENE-484553
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 363
• Identity: 125/363 - (34%)
• Similarity: 164/363 - (45%)
• Gaps: 110/363 - (30%)

  Fly   215 QNMGSLMNSGSSASDVFFSLMIQNTTKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEIS 279
            |..|...||||            |...:.:.:.:||||||||||||.||||:||:||||||||||
 Frog    16 QASGGNSNSGS------------NNQSKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEIS 68

  Fly   280 KRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKAL-RRDGYPYPMPYPSVPVE 343
            ||||||||||:|.||||||||||||||:|||||||||||||||.|.| ::|.|..|
 Frog    69 KRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP--------- 124

  Fly   344 ALRAGITPGYFAPGPTAAAYHLGSHLGQTSTPTTTQATLSGQMDKFA-------------LERSS 395
                   .|..|||.......:|:.||         |.::.:||.:|             .|:..
 Frog   125 -------GGLLAPGANPMTSGVGASLG---------AGVNQRMDTYAHMNGWTNGGYGMMQEQLG 173

  Fly   396 YLSNSSQASAYSAYLDPSVLTKAYFD--SKMYQDRAANYAFDISKIYGAQQHAAAHHQQQQQQQQ 458
            |    .|....||:..|.:.....:|  :..|...:::..:    :.|:..::.::.||
 Frog   174 Y----PQHPGLSAHNAPQMQPMHRYDVSALQYNSMSSSQTY----MNGSPTYSMSYSQQ------ 224

  Fly   459 QQQQQQQQLLLSGGGGSGGGGSASSHNNNSSSGLDDRDATPQLEAVESKPHLHSPSDVG------ 517
                        |..|...|...|...:.|||       :|.:  |.|..|..:|...|
 Frog   225 ------------GAPGMSLGSMGSVVKSESSS-------SPPV--VTSSSHSRAPCQAGDLRDMI 268

  Fly   518 ---LDYAQ-----------YAQQYGGQLAAAAGGAVGG 541
               |..|:           .:|.|  |.|:.||.|:.|
 Frog   269 SMYLPGAEVPEPAAQSRLHMSQHY--QSASVAGTAING 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	62/70 (89%)
sox2	NP_998869.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		8/35 (23%)
		SOX-TCF_HMG-box	36..107	CDD:238684	62/70 (89%)
		SOXp	106..194	CDD:372055	28/116 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	232..259		9/35 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I4121
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm49198
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.060