Protein Alignment Sox21b and Sox17

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001101372.1
• Gene: Sox17 / 312936
• RGDID: 1305371
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 427
• Identity: 117/427 - (27%)
• Similarity: 164/427 - (38%)
• Gaps: 129/427 - (30%)

  Fly   178 GAANSHHSAPASSSVMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTKR 242
            |.|:...|.|.|:.....|...........|.:.::......:.:||:.|.         .:::.
  Rat     7 GYASDDQSQPRSAQPAVMAGLGPCPWAESLSSLGDVKVKGEVVASSGAPAG---------TSSRA 62

  Fly   243 QNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAM 307
            :.|..|:|||||||||::.:|:::||.||.:||:|:||.||..||.||..|||||::||:|||..
  Rat    63 KAESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQ 127

  Fly   308 HMKEHPDYKYRPRRKP--KALRR--------------------------DGYPYPMPYPSVPVEA 344
            ||::||:|||||||:.  |.::|                          ||...|.|.|..|.
  Rat   128 HMQDHPNYKYRPRRRKQVKRMKRVEGGFLHALAEPQAGALGPEGGRVAMDGLGLPFPEPGYPA-- 190

  Fly   345 LRAGITPGYFAPGPTAAAYHLGSH------LGQTS-----TPTTTQATLSGQMDKFALERSSYLS 398
                        ||...:.|:|:|      ||..:     .||...:.|.|.....|...:....
  Rat   191 ------------GPPLMSPHMGAHYRDCQGLGAPALDGYPLPTPDTSPLDGVEQDPAFFAAPLPG 243

  Fly   399 NSSQASAY-----SAYL--------------DPSVLTKAYFDSKMYQDRAANYAFDISKIYGAQQ 444
            :...|.||     |.|.              |||       .|.|....|...|..:  .|||..
  Rat   244 DCPAAGAYTYAQVSDYAVPAEPSAGPMRVGPDPS-------GSAMPGILAPPSALHL--YYGAMG 299

  Fly   445 HAAA-----HHQQQQQQQQQQ---------QQQQQQLLLSGGGGSGGGGSASSHNNNSSSGLDDR 495
            ..||     .|.|.||..|.|         ..||..        :.|.|..|.    ....|..|
  Rat   300 SPAASAGRGFHAQPQQPLQPQPPPPPPPPPPPQQHP--------THGPGQPSP----PPEALPCR 352

  Fly   496 DATP---------QLEAVESKPHLH---SPSDVGLDY 520
            |.|.         :::..|.:.:||   .| ::||.|
  Rat   353 DGTEPNQPTELLGEVDRTEFEQYLHFVYKP-EMGLPY 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	42/70 (60%)
Sox17	NP_001101372.1	SOX-TCF_HMG-box	67..138	CDD:238684	42/70 (60%)
		Sox17_18_mid	203..253	CDD:403331	10/49 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910