Protein Alignment Sox21b and Sox18

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001019952.1
• Gene: Sox18 / 311723
• RGDID: 1311718
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 272
• Identity: 90/272 - (33%)
• Similarity: 128/272 - (47%)
• Gaps: 48/272 - (17%)

  Fly   178 GAANSHHSAPASS-SVMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTK 241
            |||......|.:: |..:.|:.:.|..:...||.|..: ..|                  :...:
  Rat    27 GAAAEPRGLPVTNVSPTSPASPSSLPRSPPRSPESGRY-GFG------------------RGERQ 72

  Fly   242 RQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRA 306
            ..:|..|:|||||||||::.:|:::||.||.:||:.:||.||..||.|...|||||::||:|||.
  Rat    73 TADELRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNTAEKRPFVEEAERLRV 137

  Fly   307 MHMKEHPDYKYRPRRKPKA--LRR--DGYPYP-MPYPSVPVEALRAGI-TPGYFAPGPTAAAYHL 365
            .|:::||:||||||||.:|  :||  .|...| :..||.|.|...|.. :...|...||     |
  Rat   138 QHLRDHPNYKYRPRRKKQARKVRRLEPGLLLPGLVQPSAPPEPFAAASGSARSFRELPT-----L 197

  Fly   366 GSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAA 430
            |:.......||..::.|.|      ||       |.:||.:...|.|.......|.:..    |.
  Rat   198 GAEFDGLGLPTPERSPLDG------LE-------SGEASFFPPPLAPEDCALRAFRAPY----AP 245

  Fly   431 NYAFDISKIYGA 442
            ..|.|.|..||:
  Rat   246 ELARDPSFCYGS 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	45/78 (58%)
Sox18	NP_001019952.1	HMG-box_SoxF_SOX18	76..155	CDD:438851	46/78 (59%)
		Sox17_18_mid	191..239	CDD:463454	16/65 (25%)