DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sox21b and Sox18

DIOPT Version :9

Sequence 1:NP_001261829.1 Gene:Sox21b / 39569 FlyBaseID:FBgn0042630 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001019952.1 Gene:Sox18 / 311723 RGDID:1311718 Length:377 Species:Rattus norvegicus


Alignment Length:272 Identity:90/272 - (33%)
Similarity:128/272 - (47%) Gaps:48/272 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 GAANSHHSAPASS-SVMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTK 241
            |||......|.:: |..:.|:.:.|..:...||.|..: ..|                  :...:
  Rat    27 GAAAEPRGLPVTNVSPTSPASPSSLPRSPPRSPESGRY-GFG------------------RGERQ 72

  Fly   242 RQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRA 306
            ..:|..|:|||||||||::.:|:::||.||.:||:.:||.||..||.|...|||||::||:|||.
  Rat    73 TADELRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNTAEKRPFVEEAERLRV 137

  Fly   307 MHMKEHPDYKYRPRRKPKA--LRR--DGYPYP-MPYPSVPVEALRAGI-TPGYFAPGPTAAAYHL 365
            .|:::||:||||||||.:|  :||  .|...| :..||.|.|...|.. :...|...||     |
  Rat   138 QHLRDHPNYKYRPRRKKQARKVRRLEPGLLLPGLVQPSAPPEPFAAASGSARSFRELPT-----L 197

  Fly   366 GSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAA 430
            |:.......||..::.|.|      ||       |.:||.:...|.|.......|.:..    |.
  Rat   198 GAEFDGLGLPTPERSPLDG------LE-------SGEASFFPPPLAPEDCALRAFRAPY----AP 245

  Fly   431 NYAFDISKIYGA 442
            ..|.|.|..||:
  Rat   246 ELARDPSFCYGS 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sox21bNP_001261829.1 SOX-TCF_HMG-box 247..318 CDD:238684 39/70 (56%)
Sox18NP_001019952.1 SOX-TCF_HMG-box 78..149 CDD:238684 39/70 (56%)
Sox17_18_mid 191..239 CDD:403331 16/65 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.910

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