Protein Alignment Sox21b and Sox6

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_038962229.1
• Gene: Sox6 / 293165
• RGDID: 1309000
• Length: 855
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 128/607 - (21%)
• Similarity: 195/607 - (32%)
• Gaps: 211/607 - (34%)

  Fly    14 LSLAHPLQTHLGSGGGTHHLGQLAAAVHQQQQQQQQSDQGLGHSHHLHGQQLSLNHQHHH----- 73
            |..||..|..|.:........|:..|..||:|..:|..|.|...|.::..|..:.....|
  Rat   232 LLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQQVQGHMPPLM 296

  Fly    74 ----PHQ---------------------------------------------SP-QHQQQHQHHP 88
                ||.                                             || |.|:.|..||
  Rat   297 IPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHP 361

  Fly    89 CSSNSSNGSPNGSTGLGLHP--HSALHLAHHHSQLHQHH----------PAGQQQQHSQPPVSSS 141
            ..:....|. :...|..|.|  |...| :::|.|:.|.:          |..:.....|||.|:.
  Rat   362 QINPRLKGI-SDRLGRNLDPYEHGGGH-SYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNSAG 424

  Fly   142 STS-------------------------------------------------HHSQSQALSHQTH 157
            :.|                                                 ..|::..::....
  Rat   425 AVSPTGIKNEKRGTSPVTQVKDETTAQPLNLSSRPKTAEPVKSPTSPTQSLFPASKTSPVNLPNK 489

  Fly   158 SNGSSQLGGGSASGAGSVAGGAANSHHSAPASSSVMAAAAAA-----HLHHNSQASP-------- 209
            |:..|.:||....|:......:.||........:||.|...|     .:....|..|
  Rat   490 SSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQPHGVDGKLS 554

  Fly   210 ------ISNLH--------QNMG-----------------------------SLMNSGSSASDVF 231
                  :||..        :|:|                             ..||..::....:
  Rat   555 SMNSMGLSNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQY 619

  Fly   232 FSLMIQNTT------------KRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGA 284
            :.......|            :..:|.||||||||||||::.:||||.|..|.||||.|||.||:
  Rat   620 YCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGS 684

  Fly   285 EWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRK------PKALRRDGYPYPM-------- 335
            .||.::.:||:|:.:|..||..:|::::|:|||:||.|      .|.||...|...|
  Rat   685 RWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMR 749

  Fly   336 ------PYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQTST---PT--TTQATLSGQMDKF 389
                  ..|.:|:......:.||......|..:..:.|....||.   |:  ..|:|...:||..
  Rat   750 QFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKMDGA 814

  Fly   390 ALERSSYLSNSSQASAYSAYLD 411
            :|..:..::...:..||..|.|
  Rat   815 SLAGNDMINGEDEMEAYDDYED 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	39/70 (56%)
Sox6	XP_038962229.1	SOX-TCF_HMG-box	647..718	CDD:238684	39/70 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810