DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sox21b and Sox30

DIOPT Version :9

Sequence 1:	NP_001261829.1	Gene:	Sox21b / 39569	FlyBaseID:	FBgn0042630	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_775560.1	Gene:	Sox30 / 214105	MGIID:	1341157	Length:	782	Species:	Mus musculus

Alignment Length:	284	Identity:	76/284 - (26%)
Similarity:	111/284 - (39%)	Gaps:	85/284 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 SQPPVSSSSTSHHSQSQALSHQTHSNGSSQLGGGSASGAGSVAGGAANSHHSAPASSSVMAAAAA 198
            :|||   |:...|.|........|                :|..||.......|.|..:..:..
Mouse   274 AQPP---SAFGPHQQDLRFPLTLH----------------TVPPGARIQFQGPPPSELIRLSKV- 318

  Fly   199 AHLHHNSQASPISNLHQNMGSLMN----------------SGSSASDVFFSLMIQNTTKRQNEEH 247
                      |::.:...|.||:.                |.:...|..||        :....|
Mouse   319 ----------PLTPVPIKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFS--------KDRNGH 365

  Fly   248 IKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEH 312
            :||||||||||:|:.|..:|:.||..:|:|||.:||.||..|:||:|:|:.|||::::..|.:|.
Mouse   366 VKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEF 430

  Fly   313 PDYKYRPR---RK---------------------PKALRRDGYPYPMPYPSVPVEALRAGITPGY 353
            |.:.|:||   ||                     |..:    |||..|..||.:..|:..||
Mouse   431 PGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTI----YPYRSPTYSVVIPGLQNTIT--- 488

  Fly   354 FAPGPTAAAYHLGSHLGQTSTPTT 377
            ...|....|..|.:...|..:|.|
Mouse   489 HPVGEAPPAIQLPTPAVQRPSPIT 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	35/70 (50%)
Sox30	NP_775560.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..117
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	139..226
		SOX-TCF_HMG-box	365..435	CDD:238684	35/69 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	501..604		3/12 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..724
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	756..782
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810