Protein Alignment Sox21b and Sox6

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_006507560.1
• Gene: Sox6 / 20679
• MGIID: 98368
• Length: 828
• Species: Mus musculus
• Alignment Length: 607
• Identity: 128/607 - (21%)
• Similarity: 195/607 - (32%)
• Gaps: 211/607 - (34%)

  Fly    14 LSLAHPLQTHLGSGGGTHHLGQLAAAVHQQQQQQQQSDQGLGHSHHLHGQQLSLNHQHHH----- 73
            |..||..|..|.:........|:..|..||:|..:|..|.|...|.::..|..:.....|
Mouse   205 LLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQQVQGHMPPLM 269

  Fly    74 ----PHQ---------------------------------------------SP-QHQQQHQHHP 88
                ||.                                             || |.|:.|..||
Mouse   270 IPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHP 334

  Fly    89 CSSNSSNGSPNGSTGLGLHP--HSALHLAHHHSQLHQHH----------PAGQQQQHSQPPVSSS 141
            ..:....|. :...|..|.|  |...| :::|.|:.|.:          |..:.....|||.|:.
Mouse   335 QINPRLKGI-SDRFGRNLDPSEHGGGH-SYNHRQIEQLYAAQLASMQVSPGAKMPSTPQPPNSAG 397

  Fly   142 STS-------------------------------------------------HHSQSQALSHQTH 157
            :.|                                                 ..|::..::....
Mouse   398 AVSPTGIKNEKRGTSPVTQVKDETTAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNK 462

  Fly   158 SNGSSQLGGGSASGAGSVAGGAANSHHSAPASSSVMAAAAAA-----HLHHNSQASP-------- 209
            |:..|.:||....|:......:.||........:||.|...|     .:....|..|
Mouse   463 SSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQPHGVDGKLS 527

  Fly   210 ------ISNLH--------QNMG-----------------------------SLMNSGSSASDVF 231
                  :||..        :|:|                             ..||..::....:
Mouse   528 SMNNMGLSNCRTEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQY 592

  Fly   232 FSLMIQNTT------------KRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGA 284
            :.......|            :..:|.||||||||||||::.:||||.|..|.||||.|||.||:
Mouse   593 YCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGS 657

  Fly   285 EWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRK------PKALRRDGYPYPM-------- 335
            .||.::.:||:|:.:|..||..:|::::|:|||:||.|      .|.||...|...|
Mouse   658 RWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMR 722

  Fly   336 ------PYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQTST---PT--TTQATLSGQMDKF 389
                  ..|.:|:......:.||......|..:..:.|....||.   |:  ..|:|...:||..
Mouse   723 QFFTVGQQPQMPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKMDGA 787

  Fly   390 ALERSSYLSNSSQASAYSAYLD 411
            :|..:..::...:..||..|.|
Mouse   788 SLAGNDMINGEDEMEAYDDYED 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	39/70 (56%)
Sox6	XP_006507560.1	SOX-TCF_HMG-box	620..691	CDD:238684	39/70 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810