Protein Alignment Sox21b and Sox3

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_033263.2
• Gene: Sox3 / 20675
• MGIID: 98365
• Length: 450
• Species: Mus musculus
• Alignment Length: 484
• Identity: 147/484 - (30%)
• Similarity: 189/484 - (39%)
• Gaps: 157/484 - (32%)

  Fly   125 HPAGQQQQHSQPPVSSSSTSHHSQSQALSHQTHSNGSSQLGGGSASGAGSVAGGAANSHHSAPAS 189
            :|.|       ||..::.|...:...|..    .:|::..||.:|...||   |.||
Mouse    86 NPVG-------PPTPAAGTGVPAAPGAAG----KSGANPAGGANAGNGGS---GGAN-------- 128

  Fly   190 SSVMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTKRQNEEHIKRPMNA 254
                                        |.....|...||               ::.:||||||
Mouse   129 ----------------------------GGGGGGGGGGSD---------------QDRVKRPMNA 150

  Fly   255 FMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRP 319
            ||||||.||||:|.:|||||||||||||||:|||||:.||||||||||||||:||||:|||||||
Mouse   151 FMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRP 215

  Fly   320 RRKPKA-LRRDGYPYPMPYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQTS---------T 374
            |||.|. |::|.|..|            .|:.|    ||..|||....:....:|         |
Mouse   216 RRKTKTLLKKDKYSLP------------GGLLP----PGAAAAAAAAAAAAAASSPVGVGQRLDT 264

  Fly   375 PTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAANYAFDISKI 439
            .|......:|.. ....|:..|    :|..:.|:...|..|      .:|::...|...:.....
Mouse   265 YTHVNGWANGAY-SLVQEQLGY----AQPPSMSSPPPPPAL------PQMHRYDMAGLQYSPMMP 318

  Fly   440 YGAQQH--AAAHHQQQQQQQQQQQQQQQQLLLSGGGGSGGGGSASSHNNNSSSGLDDRDAT---- 498
            .|||.:  |||                     :....||.||.|.|....:::....:.||
Mouse   319 PGAQSYMNAAA---------------------AAAAASGYGGMAPSAAAAAAAAYGQQPATAAAA 362

  Fly   499 ----------PQLEAVESKPHLHSPSDVGLDYAQYA---------QQY---GGQLAAAAGGAVGG 541
                      |....|:|:|  .||......::|.|         ..|   ||..|.||....||
Mouse   363 AAAAAAMSLGPMGSVVKSEP--SSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGG 425

  Fly   542 GAAGAAGGSAGGGSGGATAADFRRPLTVI 570
            ...|......|.|    ||.:...|||.|
Mouse   426 RLHGVHQHYQGAG----TAVNGTVPLTHI 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	59/70 (84%)
Sox3	NP_033263.2	SOX-TCF_HMG-box	143..214	CDD:238684	59/70 (84%)
		SOXp	213..306	CDD:289133	29/119 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870