Protein Alignment Sox21b and sox-2

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_741836.1
• Gene: sox-2 / 181002
• WormBaseID: WBGene00004949
• Length: 283
• Species: Caenorhabditis elegans
• Alignment Length: 280
• Identity: 112/280 - (40%)
• Similarity: 152/280 - (54%)
• Gaps: 52/280 - (18%)

  Fly   203 HNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTK--RQNEEHIKRPMNAFMVWSRLQRRK 265
            |....|..:.|.|:|...:::|..:.|        :|.|  ::|::.:||||||||||||.||:|
 Worm    21 HMPPTSSTNLLPQSMPDDLSNGPDSPD--------STGKDGKKNDDRVKRPMNAFMVWSRGQRKK 77

  Fly   266 IAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKAL-RRD 329
            :|.:||||||||||||||.|||:|:|:||||||||||||||:|||||||||||||||.|:: :::
 Worm    78 MALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKKN 142

  Fly   330 GYPYPM-----PYPSVPVEALRAGITPGY-----FAPGPT---------AAAYHLGSHLGQTSTP 375
            |.|.|.     ..||.|........|..|     |||.||         :..|.:.|.....|:|
 Worm   143 GAPIPFGNLDTKTPSYPTLTTNWNATNQYIDQFRFAPYPTTTVMDQIPFSLTYPVHSVPTDNSSP 207

  Fly   376 TTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLT------KAYF----DSKMYQDRAA 430
            :..|.  |.....||   .|||:..|::|...:  |.:|.|      :||:    |..||.
 Worm   208 SQFQP--SPMSTNFA---GSYLTPKSESSPVGS--DSTVGTVDSSQFRAYYDHTKDQMMYP---- 261

  Fly   431 NYAFDISKIYGAQQHAAAHH 450
             |:.:::.....|...:..|
 Worm   262 -YSIELTHAQNIQNALSQSH 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	58/70 (83%)
sox-2	NP_741836.1	SOX-TCF_HMG-box	59..130	CDD:238684	58/70 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040