Protein Alignment Sox21b and sem-2

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_740846.1
• Gene: sem-2 / 172162
• WormBaseID: WBGene00004771
• Length: 404
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 132/467 - (28%)
• Similarity: 182/467 - (38%)
• Gaps: 155/467 - (33%)

  Fly   133 HSQPPVS--------SSSTSHHSQSQALSHQTHSNGSSQLGGGSASGAGSVAGGAANSHHSAPAS 189
            |..||::        :||||                    |..:|:.:.|||......||.
 Worm    18 HMMPPINWAAAAIAVASSTS--------------------GATNATSSNSVATSQQLQHHP---- 58

  Fly   190 SSVMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTKRQNEEHIKRPMNA 254
                ...||....|..||.|            .|.:..||.        |..:::..||||||||
 Worm    59 ----YGTAAGGYKHAQQAIP------------KSVTPYSDA--------TNCKKSSNHIKRPMNA 99

  Fly   255 FMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRP 319
            |||||:::||||.:..|.|||:||||:||:.|:.||:|||.||:.||:|||..||:|:|||||:|
 Worm   100 FMVWSQMERRKICEHQPDMHNAEISKQLGSRWRSLTDEEKAPFVAEAERLRVCHMQEYPDYKYKP 164

  Fly   320 RRKPKALRRDGYPYPMPYPSVP--VEALRAGITPGYFAPGPTAAAYHLGSHLGQTSTPTTTQATL 382
            |:|||. ..||.......|..|  .:|...|.:|                ...|...|.|.|.:.
 Worm   165 RKKPKK-NPDGTLQQPAQPQAPQQQQAPPRGASP----------------QARQRKRPNTDQQSE 212

  Fly   383 SGQMDKFALER-------SSYLSNSSQASAYSAYLDPSVLTKAYF--DSKMYQDRAANYAFDISK 438
            :.|...|...:       ::::|::.:...:.:|..||....|..  :|..|.|
 Worm   213 TQQFQNFKSVKVEQDWMGNAHMSHAQKMPFHPSYPSPSEFGHAPLTPESGFYDD----------- 266

  Fly   439 IYGAQQHAAAHHQQQQQQQQQQQQQQQQLLLSGGGGSGGGGSASSHNNNSSSGLD------DRDA 497
             |..||    ||||.                          .||.|:|::.|.|.      |...
 Worm   267 -YFTQQ----HHQQH--------------------------FASQHHNSAGSPLRMTNLGMDMGM 300

  Fly   498 TPQLEAVES------KP-HLH-SPSDVGLDYAQYAQQYGGQLAAAAGGAVGGGAAGAAGGSAGG- 553
            .||:....|      .| :|| ||..|..|          .:.:.:.|:.|.....|:..|...
 Worm   301 PPQMMGHNSGFGAGNHPFYLHTSPPSVDQD----------DMRSLSSGSSGYADCSASEQSTSSP 355

  Fly   554 GSGG----ATAA 561
            .|.|    ||||
 Worm   356 NSAGVVTMATAA 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	52/78 (67%)
sem-2	NP_740846.1	HMG-box_SoxC	92..159	CDD:438838	43/66 (65%)