Protein Alignment Sox21b and HMG20A

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_060670.1
• Gene: HMG20A / 10363
• HGNCID: 5001
• Length: 347
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 73/392 - (18%)
• Similarity: 133/392 - (33%)
• Gaps: 151/392 - (38%)

  Fly   182 SHHSAPASSSVMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSS-ASDVFFSLMIQNTTKRQNE 245
            :|...|.||...::.      :|.:.  :.:|.|  |.|:.|.|| |::       .|..:.::|
Human    32 NHPEVPYSSGATSST------NNPEF--VEDLSQ--GQLLQSESSNAAE-------GNEQRHEDE 79

  Fly   246 EHIKR---------------------PMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLL 289
            :..||                     |:..::.:...:|.::....|::...||::.||.||..|
Human    80 QRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKL 144

  Fly   290 TEEEKRPFIDEAKRLRAMHMKEHPDY-----------KYRPRRKPKALRRDGYPYPMPYPSVPVE 343
            ..|||:.::|||.|.:..:|||...|           |.:.|:|.|:.|:|
Human   145 PPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQD-------------- 195

  Fly   344 ALRAGITPGYFAPGPTAAAYHLGSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSA 408
                                            ...|||...:.:....|||.:
Human   196 --------------------------------AARQATHDHEKETEVKERSVF------------ 216

  Fly   409 YLDPSVLTKAYF------DSKMYQDRAANYAFDISKIYGAQQHAAA-------------HHQQQQ 454
              |..:.|:.:.      ::::.|.|.:|..|: .:....|:|..:             ..:.:.
Human   217 --DIPIFTEEFLNHSKAREAELRQLRKSNMEFE-ERNAALQKHVESMRTAVEKLEVDVIQERSRN 278

  Fly   455 QQQQQQQQQQQQLLLSGGGGSGGGGSASSHNNNSSSGLDDRDATPQLEAVES-KPHLHS-----P 513
            ...||..:..:|:|.|               :.:|..|.....||.::.::| ...|||     |
Human   279 TVLQQHLETLRQVLTS---------------SFASMPLPGSGETPTVDTIDSYMNRLHSIILANP 328

  Fly   514 SD 515
            .|
Human   329 QD 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	26/110 (24%)
HMG20A	NP_060670.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..113		18/97 (19%)
		DUF5401	<59..313	CDD:375164	59/336 (18%)
		HMG-box_HMG20A	83..186	CDD:438833	24/102 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..211		9/77 (12%)