Protein Alignment Sox21b and sox8a

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001271361.1
• Gene: sox8a / 102216265
• ZFINID: ZDB-GENE-130530-719
• Length: 401
• Species: Danio rerio
• Alignment Length: 309
• Identity: 88/309 - (28%)
• Similarity: 141/309 - (45%)
• Gaps: 69/309 - (22%)

  Fly   236 IQNTTKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDE 300
            :|.:...:::.|:||||||||||::..|||:|...|.:||:|:||.||..|:||:|.|||||::|
Zfish    74 MQGSRSLKDKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEE 138

  Fly   301 AKRLRAMHMKEHPDYKYRPRR----KPKALRRDGYPYPMPYPSVPVEALRAGITPGYFAPGPTAA 361
            |:|||..|.|::|||||:|||    ||.....:.......:.:.|:....||:          .|
Zfish   139 AERLRLQHKKDYPDYKYQPRRRKSLKPGQNEAEAGAEKNLHHTDPIYKTEAGM----------RA 193

  Fly   362 AYHLGSH----LGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDS 422
            .:|...|    .|..:.|||.::.....|.:        ||.:::.:...:.:|.|.|:.....|
Zfish   194 MHHQTIHGVQPHGPPTPPTTPKSDQHQSMKR--------LSENARQNIDFSNVDISELSSDVIGS 250

  Fly   423 KMYQDRAANYAFDISKIYGAQQHAAAHHQQQQQQQQQQQQQQQQLLLSGGGGSGGGG-------S 480
            ..        .||:                        ::..|.|.|:|...||||.       |
Zfish   251 IS--------QFDV------------------------REFDQYLPLNGHTESGGGQHSSPGCFS 283

  Fly   481 ASSHNNNSSSGLDDRDATPQL-EAVESKPHLHSPSDVGLDYAQYAQQYG 528
            .|.|:::.:|..:....:|.. .|.:.:|.:.:..   |..:.|.|.:|
Zfish   284 TSFHHHSGASAWNKPSGSPSTSSANQQRPLIKTEQ---LSPSHYGQSHG 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	49/82 (60%)
sox8a	NP_001271361.1	Sox_N	<47..73	CDD:463586
		HMG-box_SoxE	85..159	CDD:438840	45/73 (62%)