Protein Alignment Sox21b and sox8

DIOPT Version :9

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_002932315.2
• Gene: sox8 / 100497725
• XenbaseID: XB-GENE-480865
• Length: 466
• Species: Xenopus tropicalis
• Alignment Length: 464
• Identity: 117/464 - (25%)
• Similarity: 176/464 - (37%)
• Gaps: 151/464 - (32%)

  Fly   127 AGQQQQHSQPPVSSSSTSHHSQSQALSHQTHSNGSSQLGGGSASGAGSVAGGAANSHHSAPASSS 191
            :.:|:...:||.|.:.|     :.::||.:.|:..|.|....:.|.||         |..|.
 Frog     5 SSEQEHVPEPPCSPTGT-----ASSMSHVSDSDSDSPLSPAGSEGRGS---------HRPPG--- 52

  Fly   192 VMAAAAAAHLHHNSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTKR-------------- 242
                              ||.|.:      ..|....|..|...|:....:
 Frog    53 ------------------ISQLSK------RDGEETMDERFPACIREAVSQVLKGYDWSLVPMPV 93

  Fly   243 ------QNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEA 301
                  :.:.|:||||||||||::..|||:|...|.:||:|:||.||..|:||:|.|||||::||
 Frog    94 RGSGGLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSENEKRPFVEEA 158

  Fly   302 KRLRAMHMKEHPDYKYRPRRK--PKALRRDGYPYPMPYPSVPVEALRAG-----ITPGYFAPGPT 359
            :|||..|.|:||||||:|||:  .||.:.|.       .|.....|..|     ...|..:.|..
 Frog   159 ERLRVQHKKDHPDYKYQPRRRKSAKAGQSDS-------DSGAELGLHGGSQMYKSDSGMGSMGEN 216

  Fly   360 -AAAYHLGSHLGQTSTPTTTQATL-SGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDS 422
             ..:.|.|.:.|..:.|||.:..| .|...:...|....:.:..|...:| .:|.|.|:....::
 Frog   217 HLHSEHAGQNHGPPTPPTTPKTDLHHGGKQELKHEGRRMMESGRQNIDFS-NVDISELSSEVINN 280

  Fly   423 KMYQDRAANYAFDISKIYGAQQHAAAHHQQQQQQQQQQQQQQQQLLLSGGG------GSGG---- 477
                    ..|||:.:.                        .|.|.|:|.|      |...
 Frog   281 --------IEAFDVHEF------------------------DQYLPLNGHGPIPADHGQNATAAP 313

  Fly   478 ---------GGSAS---SHNNNSSSGLDDRDATPQLEAVESKPHLH----SPSDVG--------- 517
                     |.:|:   ||.:.|:|      ::...|:.:.:||:.    |||...
 Frog   314 YASSYTHAPGATAAPVWSHKSPSTS------SSSSSESGQQRPHIKTEQLSPSHYNDQSQGSPTH 372

  Fly   518 LDYAQYAQQ 526
            .||..|:.|
 Frog   373 SDYNTYSAQ 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	44/70 (63%)
sox8	XP_002932315.2	Sox_N	<39..94	CDD:372113	12/90 (13%)
		SOX-TCF_HMG-box	104..174	CDD:238684	43/69 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910