Protein Alignment Sox21b and sox6

DIOPT Version :10

• Sequence 1: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_031755685.1
• Gene: sox6 / 100144640
• XenbaseID: XB-GENE-483934
• Length: 804
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 130/584 - (22%)
• Similarity: 201/584 - (34%)
• Gaps: 180/584 - (30%)

  Fly    14 LSLAHPLQTHLGSGGGTHHLGQLAAAVHQQQQQQQQSDQGLGHSHHLHGQQLSLNHQHH------ 72
            |..||..|..|.:........|:..|..||:|..:|..|.|...|.::..|..:..|.|
 Frog   233 LLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINILQQQIQVQGHMPPLMI 297

  Fly    73 --HPHQ---------------------------------------------SP-QHQQQHQHHPC 89
              .||.                                             || |.||.:.....
 Frog   298 PIFPHDQRTLAAAAAAQQGFLFPPGLSYKPGDNYPMQFIPSTMAAAAASGLSPLQLQQLYAAQLA 362

  Fly    90 SSNSSNGSPNGSTGLGLHPHSALHLAHHHSQLHQHHPAGQ-QQQHSQP-----------PVSSSS 142
            |...|.|:...:|....:....|......|:.....|..| :.:.:||           |:.|.:
 Frog   363 SMQVSPGAKIPTTPQPANAPGTLSPTGMKSEKRGTSPVAQIKDEAAQPLNLSARPKTADPIKSPT 427

  Fly   143 TSHH-----SQSQALSHQTHSNGSSQLGGGSASGAGSVAGGAANSHHSAPA----SSSVMAAAAA 198
            :...     |::..:|....|...|.:.|.|.....|:         ::||    ..:||.|...
 Frog   428 SPTQSFFPVSKTSPVSLSNKSGIPSPIRGPSLDILSSL---------NSPALFGDQDTVMKAIQE 483

  Fly   199 AHL-------------HHNSQASPISNL------------------------------HQNMGSL 220
            |..             |......||:|:                              .:|:|..
 Frog   484 ARKMREQIQREQLLTPHSIDGKLPINNMGLNNCRSDKMLLDAVTGKICIRSAHTERTHFENLGPQ 548

  Fly   221 MNS--------GSSASD------------VFFSLMIQNTTKRQNEE-HIKRPMNAFMVWSRLQRR 264
            :..        |....|            |..:.:.::|..|.:.| ||||||||||||::.:||
 Frog   549 LTGKPNEDGKLGPGVIDLTRPEDVEGGATVVEARVYRDTRGRSSSEPHIKRPMNAFMVWAKDERR 613

  Fly   265 KIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRK------P 323
            ||.|..|.||||.|||.||:.||.::.:||:|:.:|..||..:|::::|:|||:||.|      .
 Frog   614 KILQAFPDMHNSNISKILGSRWKAMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDG 678

  Fly   324 KALRRDGYPYPM--------------PYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQTST 374
            |.||...|...|              ..|.:|:......:.||..:...|..:..:.|....||.
 Frog   679 KKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPISTPTGVVYPGTISMATTTPSPQMTSDCSSTSA 743

  Fly   375 ---PT--TTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAYFDSKMYQDRAANYA 433
               |:  ..|:|...::|..:|..:..::...:...|..:.|.   .|:.:.|    |..||.|
 Frog   744 SPEPSIPVIQSTYGMKLDSGSLGGNDLMNGEDEMEMYDDFEDD---PKSDYSS----DNEANEA 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	44/85 (52%)
sox6	XP_031755685.1	HMG-box_EGL13-like	595..672	CDD:438848	42/76 (55%)