Protein Alignment Sox21a and SOX13

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_005677.2
• Gene: SOX13 / 9580
• HGNCID: 11192
• Length: 622
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 73/218 - (33%)
• Similarity: 100/218 - (45%)
• Gaps: 60/218 - (27%)

  Fly     4 ISALLHRSHSHSNGYTSSGSSNHSHSSSLSPQLPGINLGLGMVGGLGMGMSV------------- 55
            :|:.:.|..||      .|.:....||  .|.||        :|.||.|.:|
Human   315 MSSCVPRPPSH------GGPTRDLQSS--PPSLP--------LGFLGEGDAVTKAIQDARQLLHS 363

  Fly    56 --GVGSGSGNT-----------TPPPMPPADLAVPPAAPTPVAPKMHQHTHHHGNSHHNAPTSHS 107
              |...||.||           :|......|..|.|.....::..|      .|:.|.  |.|.:
Human   364 HSGALDGSPNTPFRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDM------DGSRHF--PESRN 420

  Fly   108 NSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFID 172
            :|          ||||||||||||::.:|||:.|..|.||||.|||.||:.||.:|..:|:|:.:
Human   421 SS----------HIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYE 475

  Fly   173 EAKRLRALHMKEHPDYKYRPRRK 195
            |..||...|::::|||||:||.|
Human   476 EQARLSRQHLEKYPDYKYKPRPK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	43/77 (56%)
SOX13	NP_005677.2	HMG-box_SoxD	423..499	CDD:438839	43/76 (57%)