Protein Alignment Sox21a and ROX1

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_015390.1
• Gene: ROX1 / 856178
• SGDID: S000006269
• Length: 368
• Species: Saccharomyces cerevisiae
• Alignment Length: 370
• Identity: 83/370 - (22%)
• Similarity: 125/370 - (33%)
• Gaps: 116/370 - (31%)

  Fly   116 NSHDHIKRPMNAFMVWSRGQRRKM-----AQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAK 175
            :|...|.||.|||:::.:...|.:     ||.....|||.|||.:|.:||.|....|..:.:.|:
Yeast     5 SSTPKIPRPKNAFILFRQHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAE 69

  Fly   176 RLRALHMKEHPDYKYRPRRKPKTLN---------------------------KSPVPGGGGGGGG 213
            :.:..|.:::|:|||:|.||.|...                           :.|.
Yeast    70 KEKLEHERKYPEYKYKPVRKSKKKQLLLKEIEQQQQQQQKEQQQQKQSQPQLQQPF--------- 125

  Fly   214 GGANGGVNAGGAGNSGPSGPGSVGSPKDMQPQLS-------------------------PL---- 249
              .|..|....|.:..||  .||.|....|.||:                         ||
Yeast   126 --NNNIVLMKRAHSLSPS--SSVSSSNSYQFQLNNDLKRLPIPSVNTSNYMVSRSLSGLPLTHDK 186

  Fly   250 -GQSLPHLHGHPHQSPYQSHPHHPHPHPHHVQLAAATLSAKYGFGSPLELSLPRLP---NAFPGL 310
             .:.||.|....:..||.|.||.|....|::.:|.|         .|...|.|:||   :.....
Yeast   187 TARDLPQLSSQLNSIPYYSAPHDPSTRHHYLNVAQA---------QPRANSTPQLPFISSIINNS 242

  Fly   311 AHYPLDPTLALDLQAR--------------LQAMYAGSIYHPWRYLPLISPETPPSPPSSSGTGI 361
            :..|:..|......|.              |:.....||.:..:|||      ||..||.....:
Yeast   243 SQTPVTTTTTSTTTATSSPGKFSSSPNSSVLENNRLNSINNSNQYLP------PPLLPSLQDFQL 301

  Fly   362 SSYGCVKSEKSSPNAVVASAASPPNIIXPTPLRFGAGTSSSAEHV 406
            ..|..:|  :..|..:|...:...|.:..|       |:.:..|:
Yeast   302 DQYQQLK--QMGPTYIVKPLSHTRNNLLST-------TTPTHHHI 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	25/75 (33%)
ROX1	NP_015390.1	MATA_HMG-box	9..88	CDD:238685	27/78 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.790