Protein Alignment Sox21a and SOX14

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_004180.1
• Gene: SOX14 / 8403
• HGNCID: 11193
• Length: 240
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 108/241 - (44%)
• Similarity: 120/241 - (49%)
• Gaps: 57/241 - (23%)

  Fly   119 DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMK 183
            |||||||||||||||||||||||:||||||||||||||||||||:|.:|||:|||||||||.|||
Human     6 DHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMK 70

  Fly   184 EHPDYKYRPRRKPKTLNKS-----PVPGGGGGGGGGGANGGVNAGGAGNSGP----------SGP 233
            ||||||||||||||.|.|.     |:|..|.......|...|.|.....|.|          |.|
Human    71 EHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKARAFLPPASAP 135

  Fly   234 GSVGSPKDMQ-------------------PQLSPLGQ--------SLPHLHGHPHQSPYQSHPHH 271
            .|:..|....                   |..|.||.        |.|..|.|.|.||
Human   136 YSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSP------- 193

  Fly   272 PHPHPHHVQLAAATLSAKYGFGSPLELSLPRLPNAFPGLAHYPLDP 317
              .:|.:|.....|..:......|:...|      |||:....:||
Human   194 --TNPGYVVPCNCTAWSASTLQPPVAYIL------FPGMTKTGIDP 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	64/70 (91%)
SOX14	NP_004180.1	SOX-TCF_HMG-box	7..78	CDD:238684	64/70 (91%)
		SOXp	77..>118	CDD:403523	16/40 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148500
Domainoid	1	1.000	139	1.000	Domainoid score	I4785
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm41916
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	1	1.000	-	-		X1501
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.830