Protein Alignment Sox21a and SOX7

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_113627.1
• Gene: SOX7 / 83595
• HGNCID: 18196
• Length: 388
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 112/391 - (28%)
• Similarity: 154/391 - (39%)
• Gaps: 132/391 - (33%)

  Fly    77 PPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQ 141
            |||.|.|...|                            .|...|:|||||||||::.:|:::|.
Human    29 PPAVPRPPGDK----------------------------GSESRIRRPMNAFMVWAKDERKRLAV 65

  Fly   142 DNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRK--PKTLNKSPV 204
            .||.:||:|:||.||..||.||..||||::|||:|||..||:::|:||||||||  .|.|.|...
Human    66 QNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVD 130

  Fly   205 PG------------------GGGGGGGGGANGGVNAGGAG--------NSGPSGPGSVGSPKDMQ 243
            ||                  |..|..|...:.|..:.|..        :.||:|.|..|:|..:.
Human   131 PGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVD 195

  Fly   244 ---------PQLSPLGQSLPHL----------HGHPHQSPY-QSHPHHPH--PHPHHVQLAAATL 286
                     |::|||....|..          ||||.:.|: ..||:.|.  |.|.|......:|
Human   196 TYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSL 260

  Fly   287 SAKYGFGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSI----YHPW-------- 339
            :.....|..:...:|..|   |..|:|  .|.....|.:.||| :.|.:    .||.
Human   261 ALGQSPGVSMMSPVPGCP---PSPAYY--SPATYHPLHSNLQA-HLGQLSPPPEHPGFDALDQLS 319

  Fly   340 --------------RYLPLISPETPPSPPSSSGTGISSYGCVKSEKSSPNAVVASAASPPNIIXP 390
                          :||     .||..|.|::|                 |:..|...|.:.: |
Human   320 QVELLGDMDRNEFDQYL-----NTPGHPDSATG-----------------AMALSGHVPVSQVTP 362

  Fly   391 T 391
            |
Human   363 T 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	46/80 (58%)
SOX7	NP_113627.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..46		7/44 (16%)
		HMG-box_SoxF_SOX7	34..121	CDD:438849	49/114 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..197		11/56 (20%)
		Sox17_18_mid	<198..230	CDD:463454	6/31 (19%)