Protein Alignment Sox21a and SOX7

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_113627.1
• Gene: SOX7 / 83595
• HGNCID: 18196
• Length: 388
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 112/391 - (28%)
• Similarity: 154/391 - (39%)
• Gaps: 132/391 - (33%)

  Fly    77 PPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQ 141
            |||.|.|...|                            .|...|:|||||||||::.:|:::|.
Human    29 PPAVPRPPGDK----------------------------GSESRIRRPMNAFMVWAKDERKRLAV 65

  Fly   142 DNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRK--PKTLNKSPV 204
            .||.:||:|:||.||..||.||..||||::|||:|||..||:::|:||||||||  .|.|.|...
Human    66 QNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVD 130

  Fly   205 PG------------------GGGGGGGGGANGGVNAGGAG--------NSGPSGPGSVGSPKDMQ 243
            ||                  |..|..|...:.|..:.|..        :.||:|.|..|:|..:.
Human   131 PGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVD 195

  Fly   244 ---------PQLSPLGQSLPHL----------HGHPHQSPY-QSHPHHPH--PHPHHVQLAAATL 286
                     |::|||....|..          ||||.:.|: ..||:.|.  |.|.|......:|
Human   196 TYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSL 260

  Fly   287 SAKYGFGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSI----YHPW-------- 339
            :.....|..:...:|..|   |..|:|  .|.....|.:.||| :.|.:    .||.
Human   261 ALGQSPGVSMMSPVPGCP---PSPAYY--SPATYHPLHSNLQA-HLGQLSPPPEHPGFDALDQLS 319

  Fly   340 --------------RYLPLISPETPPSPPSSSGTGISSYGCVKSEKSSPNAVVASAASPPNIIXP 390
                          :||     .||..|.|::|                 |:..|...|.:.: |
Human   320 QVELLGDMDRNEFDQYL-----NTPGHPDSATG-----------------AMALSGHVPVSQVTP 362

  Fly   391 T 391
            |
Human   363 T 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	40/70 (57%)
SOX7	NP_113627.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..46		7/44 (16%)
		SOX-TCF_HMG-box	44..115	CDD:238684	40/70 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..197		11/56 (20%)
		Sox_C_TAD	198..386	CDD:288887	43/194 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148472
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.870