Protein Alignment Sox21a and SOX1

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_005977.2
• Gene: SOX1 / 6656
• HGNCID: 11189
• Length: 391
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 152/393 - (38%)
• Similarity: 182/393 - (46%)
• Gaps: 89/393 - (22%)

  Fly    88 MHQHTHHHGNSHHNAPTSHS--------------NSNTGSHHNSHDHIKRPMNAFMVWSRGQRRK 138
            |...|..|......|||:.|              ....|....:.|.:|||||||||||||||||
Human     4 MMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRK 68

  Fly   139 MAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTL---N 200
            |||:||||||||||||||||||:::|.:|||||||||||||||||||||||||||||.|||   :
Human    69 MAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKD 133

  Fly   201 KSPVPGG----GGGGGG-----------------------GGANGGVNAGGAGNSGPSGPGSVGS 238
            |..:.||    |.||||                       |||.||..|...|.:..:.||||.:
Human   134 KYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAA 198

  Fly   239 PKD----MQPQLSPLGQSLPHLHG-HPHQSPYQSHPHHPHPHPHHVQ---------LAAATLSAK 289
            ...    ||......||. |...| |||..|...||||||.|||:.|         |..:.:|..
Human   199 AAAAAAMMQEAQLAYGQH-PGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNS 262

  Fly   290 YGFGSPLELSLPRLP-------NAFPGLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISP 347
            .|:.|........||       .|..|.||    ...|:...|...|..:|::   .....|:..
Human   263 QGYMSASPSGYGGLPYGAAAAAAAAAGGAH----QNSAVAAAAAAAAASSGAL---GALGSLVKS 320

  Fly   348 E---TPPSP-------PSSSGTGISSYGCVKSEKSSPNAVVASAASPPNIIXPTPLRF---GAGT 399
            |   :||:|       |......||.| ....|...|.|..|:||.  :.:...|..:   |||.
Human   321 EPSGSPPAPAHSRAPCPGDLREMISMY-LPAGEGGDPAAAAAAAAQ--SRLHSLPQHYQGAGAGV 382

  Fly   400 SSS 402
            :.:
Human   383 NGT 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	62/70 (89%)
SOX1	NP_005977.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		9/47 (19%)
		SOX-TCF_HMG-box	50..121	CDD:238684	62/70 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..249		18/35 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4785
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.910