Protein Alignment Sox21a and sox19b

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_571777.1
• Gene: sox19b / 64812
• ZFINID: ZDB-GENE-010111-1
• Length: 293
• Species: Danio rerio
• Alignment Length: 283
• Identity: 116/283 - (40%)
• Similarity: 140/283 - (49%)
• Gaps: 61/283 - (21%)

  Fly    91 HTHHH-----------GNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNP 144
            ||..|           ||:||.:.|:     .....:..|.:||||||||||||||||||||:||
Zfish    17 HTLQHSPGMSPPGSGVGNAHHVSKTA-----CPPGVDPMDKVKRPMNAFMVWSRGQRRKMAQENP 76

  Fly   145 KMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTL-------NKS 202
            |||||||||||||||||||:.:|||||||||||||:||||:|||||:||||.|.|       .|.
Zfish    77 KMHNSEISKRLGAEWKLLTDVEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKALMKKDNSVGKY 141

  Fly   203 PVPGG-------GGGGGGGGANGGVNAGGAGN-SGPSGPGSVGSPK-----DMQPQLSPLGQSLP 254
            |:..|       ..|.||.....|...|.||. .|..| .::|.|:     |:.....|..|...
Zfish   142 PLAAGNLLASAVAQGQGGSPRMDGYGWGHAGGYMGMQG-DALGYPQQLHRYDLSALQYPAAQPYM 205

  Fly   255 HLHGHPHQSPYQSHPHHPHP-----------H-----PHHVQLA-----AATLSAKYGFGSPLEL 298
            :......|..|.|.|..|.|           |     |:|.:.|     ...:|.....|...|.
Zfish   206 NSASSYSQMSYSSSPQQPSPVMSMVKPEPLSHSPTGVPNHHRGAFQGDLRDMISMYIPGGDTSES 270

  Fly   299 SLPRLPNAFPGLAHYPLDPTLAL 321
            |..|   |:||:..:.|..|:.|
Zfish   271 SNQR---AYPGVQQHYLGGTVPL 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	68/78 (87%)
sox19b	NP_571777.1	HMG-box_SoxB	51..130	CDD:438790	68/78 (87%)
		SOXp	122..203	CDD:463537	23/81 (28%)