Protein Alignment Sox21a and sox19b

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_571777.1
• Gene: sox19b / 64812
• ZFINID: ZDB-GENE-010111-1
• Length: 293
• Species: Danio rerio
• Alignment Length: 283
• Identity: 116/283 - (40%)
• Similarity: 140/283 - (49%)
• Gaps: 61/283 - (21%)

  Fly    91 HTHHH-----------GNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNP 144
            ||..|           ||:||.:.|:     .....:..|.:||||||||||||||||||||:||
Zfish    17 HTLQHSPGMSPPGSGVGNAHHVSKTA-----CPPGVDPMDKVKRPMNAFMVWSRGQRRKMAQENP 76

  Fly   145 KMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTL-------NKS 202
            |||||||||||||||||||:.:|||||||||||||:||||:|||||:||||.|.|       .|.
Zfish    77 KMHNSEISKRLGAEWKLLTDVEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKALMKKDNSVGKY 141

  Fly   203 PVPGG-------GGGGGGGGANGGVNAGGAGN-SGPSGPGSVGSPK-----DMQPQLSPLGQSLP 254
            |:..|       ..|.||.....|...|.||. .|..| .::|.|:     |:.....|..|...
Zfish   142 PLAAGNLLASAVAQGQGGSPRMDGYGWGHAGGYMGMQG-DALGYPQQLHRYDLSALQYPAAQPYM 205

  Fly   255 HLHGHPHQSPYQSHPHHPHP-----------H-----PHHVQLA-----AATLSAKYGFGSPLEL 298
            :......|..|.|.|..|.|           |     |:|.:.|     ...:|.....|...|.
Zfish   206 NSASSYSQMSYSSSPQQPSPVMSMVKPEPLSHSPTGVPNHHRGAFQGDLRDMISMYIPGGDTSES 270

  Fly   299 SLPRLPNAFPGLAHYPLDPTLAL 321
            |..|   |:||:..:.|..|:.|
Zfish   271 SNQR---AYPGVQQHYLGGTVPL 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	62/70 (89%)
sox19b	NP_571777.1	SOX-TCF_HMG-box	52..123	CDD:238684	62/70 (89%)
		SOXp	122..203	CDD:289133	23/81 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582333
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	195	1.000	Inparanoid score	I3808
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.890