Protein Alignment Sox21a and sox12

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001025449.1
• Gene: sox12 / 562381
• ZFINID: ZDB-GENE-040724-33
• Length: 355
• Species: Danio rerio
• Alignment Length: 287
• Identity: 90/287 - (31%)
• Similarity: 125/287 - (43%)
• Gaps: 74/287 - (25%)

  Fly   120 HIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKE 184
            |||||||||||||:.:|||:.:..|.|||:|||||||..||||.:.:|.|||.||:|||..||.:
Zfish    52 HIKRPMNAFMVWSQIERRKIMEQWPDMHNAEISKRLGKRWKLLPDYEKIPFIKEAERLRLKHMAD 116

  Fly   185 HPDYKYRPRRKPK------------TLNKSPVPGGGGGGGGGG-----ANGGVNAGGAGNSGPSG 232
            :||||||||:|.|            ..:..|:||...|....|     |:.......:.|...|.
Zfish   117 YPDYKYRPRKKSKGSTPVKLGEKLPMKSSKPLPGRSSGLSCKGLKIKPASSKHKMNFSSNKYKSY 181

  Fly   233 PGSVGSPKDMQPQL-SPLGQ-----SLPHLHGHPHQSPYQSHPHHPHPHPHHVQLAAATLSAKYG 291
            ..|:.....|...| ||:.|     :..|...| .|:..||....|.|.
Zfish   182 SESMSDDDTMDVNLESPVTQQDDRNTSSHFVLH-QQATVQSEDQQPIPE---------------- 229

  Fly   292 FGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPPSPPSS 356
                |.:.:|                   :...:.:|::.:.|....:       ||:..|.|..
Zfish   230 ----LRVKVP-------------------ISQTSSIQSLSSDSECQAF-------PESTTSEPRG 264

  Fly   357 SGTGISSYGCVKSEKSSPNAVVASAAS 383
            |.:|.||    ....:|.:::|:||.|
Zfish   265 STSGRSS----TPTSTSSSSLVSSACS 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	46/70 (66%)
sox12	NP_001025449.1	SOX-TCF_HMG-box	52..123	CDD:238684	46/70 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582382
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.870