Sequence 1: | NP_001261827.1 | Gene: | Sox21a / 39567 | FlyBaseID: | FBgn0036411 | Length: | 407 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_060889.1 | Gene: | SOX18 / 54345 | HGNCID: | 11194 | Length: | 384 | Species: | Homo sapiens |
Alignment Length: | 314 | Identity: | 91/314 - (28%) |
---|---|---|---|
Similarity: | 131/314 - (41%) | Gaps: | 71/314 - (22%) |
- Green bases have known domain annotations that are detailed below.
Fly 71 PADLAVPPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQ 135
Fly 136 RRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRK----- 195
Fly 196 ----------PKTLNKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSGPGSVGSPKDMQP---QLS 247
Fly 248 PLGQSLPH---LHG-HPHQSPYQSHPHHPHP---HPHHVQLAAATLSAKYG--FGSPLELSLPRL 303
Fly 304 PNAFPGLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPPSPPSSS 357 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Sox21a | NP_001261827.1 | SOX-TCF_HMG-box | 120..191 | CDD:238684 | 38/70 (54%) |
SOX18 | NP_060889.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..88 | 10/52 (19%) | |
SOX-TCF_HMG-box | 84..155 | CDD:238684 | 38/70 (54%) | ||
Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P43680 | 87..100 | 9/12 (75%) | |||
Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P43680 | 111..123 | 6/11 (55%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 146..218 | 20/92 (22%) | |||
Important for transcriptional activation. /evidence=ECO:0000250|UniProtKB:P43680 | 166..231 | 13/85 (15%) | |||
Sox_C_TAD | 193..382 | CDD:288887 | 33/135 (24%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 293..312 | 7/17 (41%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165148451 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0527 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000028 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR10270 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R685 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
6 | 5.870 |