Protein Alignment Sox21a and Sox2

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001102651.1
• Gene: Sox2 / 499593
• RGDID: 1565646
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 134/339 - (39%)
• Similarity: 160/339 - (47%)
• Gaps: 84/339 - (24%)

  Fly    82 TPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKM 146
            |.:.|...|.....|....||..:   :..|:..||.|.:||||||||||||||||||||:||||
  Rat     7 TELKPPGPQQASGGGGGGGNATAA---ATGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKM 68

  Fly   147 HNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTL---NKSPVPGG- 207
            ||||||||||||||||:|.:|||||||||||||||||||||||||||||.|||   :|..:|||
  Rat    69 HNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGL 133

  Fly   208 ---------GGGGGGGGANGGVNAGGAGNSGPSGPGSVGSPKDMQPQLSPLGQSLPHLHGHPHQS 263
                     .|.|.|.|...|||......:..:| .|.||...||.||
  Rat   134 LAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNG-WSNGSYSMMQEQL----------------- 180

  Fly   264 PYQSHPHHP--HPH------PHH------VQLAAATLSAKYGFGSPLELSLPRLPNAFPGLAHYP 314
               .:|.||  :.|      |.|      :|..:.|.|..|..||| ..|:.......||:|
  Rat   181 ---GYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSP-TYSMSYSQQGTPGMA--- 238

  Fly   315 LDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPPSPPSSSGTGISSYGCVKSEKSS------ 373
                        |.:|  ||:         :..|...|||..:.:..|...|...:...
  Rat   239 ------------LGSM--GSV---------VKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYL 280

  Fly   374 PNAVVASAASPPNI 387
            |.|.|...|:|..:
  Rat   281 PGAEVPEPAAPSRL 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	71/78 (91%)
Sox2	NP_001102651.1	HMG-box_SoxB	41..120	CDD:438790	71/78 (91%)
		SOXp	112..202	CDD:463537	34/110 (31%)