Protein Alignment Sox21a and SoxN

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 151/491 - (30%)
• Similarity: 205/491 - (41%)
• Gaps: 154/491 - (31%)

  Fly     2 TSISALLHRSHSHSNGYTSSGSSNHSH---------SSSLSPQLPGINLGLGMVGGLGMGMSVG- 56
            ::::.|::...||   .|.|..|:|:|         ::|.||. |..:|...|...|. |..||
  Fly    35 SALAPLMNLGQSH---LTHSQLSHHNHHHHHMSAHIAASQSPN-PLSSLQSSMANTLN-GSQVGQ 94

  Fly    57 -VGSGSGNTTPPPMPPADLAVPPAA------PTPVAPKMHQHTHHHGNSHH------------NA 102
             ........:.|....::|:...::      .:||:.:.|.....||...|            .:
  Fly    95 QQQQQQQQQSSPLHSSSELSPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQHLGAGSALSSLTGGS 159

  Fly   103 PTSHSNSNTGSHHNSH-DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQ 166
            ..:::||.|.:.:..| |.:|||||||||||||||||||.||||||||||||||||:||.|:|.:
  Fly   160 SNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESE 224

  Fly   167 KRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNKSP--------VPG---GGG----------- 209
            |||||||||||||:|||||||||||||||.|||.|:.        :||   |||
  Fly   225 KRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRV 289

  Fly   210 -----------GGGGGGANGGVNAGGAGNSGPSGPGSVGSPKDMQP---------------QLSP 248
                       |.||..|.....|..|..........:.:|....|               |.|.
  Fly   290 QGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSY 354

  Fly   249 LGQ-------SLPHLHGHPH----------QSPYQSHPHHP-HPHPHHVQLAAATLSAKYGFGSP 295
            :||       .:.|::.:.:          .|||.|....| .|.|             || ||.
  Fly   355 MGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSP-------------YG-GSS 405

  Fly   296 LELSLPRLPNAFPG----------LAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETP 350
            |: ..|..|..:.|          .:|.|.|.::.                         |....
  Fly   406 LQ-QQPGSPTPYGGGGGGGGQVSCQSHSPSDSSIK-------------------------SEPVS 444

  Fly   351 PSPPS---SSGTGISSYGCVKSEKSSPNAVVASAAS 383
            |||.:   ::...|::...:|.|.||..|..|:||:
  Fly   445 PSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAA 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	61/70 (87%)
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	61/70 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451312
Domainoid	1	1.000	49	1.000	Domainoid score	I4418
eggNOG	1	0.900	-	-		E1_KOG0527
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I3128
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106862
Panther	1	1.100	-	-	P	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.740