Protein Alignment Sox21a and sox2

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_998869.1
• Gene: sox2 / 407873
• XenbaseID: XB-GENE-484553
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 291
• Identity: 128/291 - (43%)
• Similarity: 153/291 - (52%)
• Gaps: 70/291 - (24%)

  Fly   102 AP--TSHSNSNTGSHH---NSHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKL 161
            ||  .|..|||:||::   ||.|.:||||||||||||||||||||:|||||||||||||||||||
 Frog    13 APQQASGGNSNSGSNNQSKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKL 77

  Fly   162 LTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTL---NKSPVPGGGGGGGGGGANGGVNAG 223
            |:|.:|||||||||||||||||||||||||||||.|||   :|..:|||....|......||.|.
 Frog    78 LSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANPMTSGVGAS 142

  Fly   224 -GAG-----------NSGPSGPGSVGSPKDMQPQLSPLGQSLPHLHGHPHQSPYQSHPHHPHPHP 276
             |||           |...:|...:     ||.||           |:| |.|..|..:.|...|
 Frog   143 LGAGVNQRMDTYAHMNGWTNGGYGM-----MQEQL-----------GYP-QHPGLSAHNAPQMQP 190

  Fly   277 HH------VQLAAATLSAKYGFGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSI 335
            .|      :|..:.:.|..|..||| ..|:.......||::               |.:|  ||:
 Frog   191 MHRYDVSALQYNSMSSSQTYMNGSP-TYSMSYSQQGAPGMS---------------LGSM--GSV 237

  Fly   336 YHPWRYLPLISPETPPSPPSSSGTGISSYGC 366
                     :..|:..|||..:.:..|...|
 Frog   238 ---------VKSESSSSPPVVTSSSHSRAPC 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	64/70 (91%)
sox2	NP_998869.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		12/26 (46%)
		SOX-TCF_HMG-box	36..107	CDD:238684	64/70 (91%)
		SOXp	106..194	CDD:372055	34/104 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	232..259		8/37 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I4714
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm49139
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.010