DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sox21a and sox21b

DIOPT Version :9

Sequence 1:NP_001261827.1 Gene:Sox21a / 39567 FlyBaseID:FBgn0036411 Length:407 Species:Drosophila melanogaster
Sequence 2:NP_001009888.1 Gene:sox21b / 406246 ZFINID:ZDB-GENE-040429-1 Length:245 Species:Danio rerio


Alignment Length:247 Identity:114/247 - (46%)
Similarity:127/247 - (51%) Gaps:63/247 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMK 183
            ||:||||||||||||.|||||||:||||||||||||||||||||||.:|||||||||||||:|||
Zfish     6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMK 70

  Fly   184 EHPDYKYRPRRKPKTLNKS-----PVPGGGG-------GGGGGGA-------NGGVNAGGAG--- 226
            ||||||||||||||||.|.     ||....|       ||...||       |....|..|.   
Zfish    71 EHPDYKYRPRRKPKTLMKKDKFAFPVAYNLGEHEALKVGGLPAGALTESLMSNPDKAAAAAAAAA 135

  Fly   227 ---------NSGPSGPGSVGSP-KDMQP----QLSPLGQSL------------PHLHGHPHQSPY 265
                     ::.|.....:||. .::.|    ..||||...            .|.|.|.|.|| 
Zfish   136 ARVFFNPSMSANPYSFFDLGSKMTELSPPSFSYASPLGYPTAATAFSGAVGGGAHTHTHSHPSP- 199

  Fly   266 QSHPHHPHPHPHHVQLAAATLSAKYGFGSPLELSLPRLPNAFPGLAHYPLDP 317
             .:|.:..|..     .||..||  |...||...|      .||:....|:|
Zfish   200 -GNPGYMIPCN-----CAAWPSA--GLQPPLAYIL------LPGMGKPQLEP 237

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sox21aNP_001261827.1 SOX-TCF_HMG-box 120..191 CDD:238684 64/70 (91%)
sox21bNP_001009888.1 SOX-TCF_HMG-box 7..78 CDD:238684 64/70 (91%)
SOXp 77..>95 CDD:289133 11/17 (65%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 1 1.000 - - otm25204
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R685
SonicParanoid 1 1.000 - - X1501
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
87.900

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