Protein Alignment Sox21a and Sox21b

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 462
• Identity: 138/462 - (29%)
• Similarity: 170/462 - (36%)
• Gaps: 223/462 - (48%)

  Fly     8 LHRSHSHSNGY----------------TSSGSSNHSHSSSLSPQLPGINLGLGMVGGLGMGMSVG 56
            ||.:|.||..:                :||.:|:||.|.:||.|..  :.|...:||   |.:.|
  Fly   112 LHLAHHHSQLHQHHPAGQQQQHSQPPVSSSSTSHHSQSQALSHQTH--SNGSSQLGG---GSASG 171

  Fly    57 VGS---GSGNTTPPPMPPADLAVPPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNS- 117
            .||   |:.|:...         .||:.:.:|.....|.||:..:   :|.|:.:.|.||..||
  Fly   172 AGSVAGGAANSHHS---------APASSSVMAAAAAAHLHHNSQA---SPISNLHQNMGSLMNSG 224

  Fly   118 --------------------HDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLL 162
                                .:||||||||||||||.||||:|||||||||||||||||||||||
  Fly   225 SSASDVFFSLMIQNTTKRQNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLL 289

  Fly   163 TEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNKS----PVP------------------ 205
            ||.:|||||||||||||:|||||||||||||||||.|.:.    |:|
  Fly   290 TEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALRRDGYPYPMPYPSVPVEALRAGITPGYF 354

  Fly   206 ----------------------------------------------------------------- 205
                                                                             
  Fly   355 APGPTAAAYHLGSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDPSVLTKAY 419

  Fly   206 ---------------------------------------------------GGGGGGGGGGANGG 219
                                                               ||||.||||.|:..
  Fly   420 FDSKMYQDRAANYAFDISKIYGAQQHAAAHHQQQQQQQQQQQQQQQQLLLSGGGGSGGGGSASSH 484

  Fly   220 VNAGGAGNSGPSGPGSVGSPKDMQPQLSPLGQSLPHLHGHPHQSPYQSHPHHPHPHPHHVQLAAA 284
            .|...:|.          ..:|..|||..: :|.||||.                 |..|.|..|
  Fly   485 NNNSSSGL----------DDRDATPQLEAV-ESKPHLHS-----------------PSDVGLDYA 521

  Fly   285 TLSAKYG 291
            ..:.:||
  Fly   522 QYAQQYG 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	65/70 (93%)
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	65/70 (93%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451321
Domainoid	1	1.000	49	1.000	Domainoid score	I4418
eggNOG	1	0.900	-	-		E1_KOG0527
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I3128
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.870