Protein Alignment Sox21a and Sox17

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001101372.1
• Gene: Sox17 / 312936
• RGDID: 1305371
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 107/334 - (32%)
• Similarity: 144/334 - (43%)
• Gaps: 65/334 - (19%)

  Fly   104 TSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKR 168
            :|.:.:.|.|...:...|:|||||||||::.:|:::||.||.:||:|:||.||..||.||..:||
  Rat    51 SSGAPAGTSSRAKAESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKR 115

  Fly   169 PFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNKSPVPGG-------GGGGGGGGANGGVNAGGAG 226
            ||::||:|||..||::||:|||||||:.:......|.||       ...|..|...|.|...|.|
  Rat   116 PFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRMKRVEGGFLHALAEPQAGALGPEGGRVAMDGLG 180

  Fly   227 NSGPSGPGSVGSPKDMQPQLSP-----LGQSLPHLHGHPHQSP--------YQSHPHHPHPHPHH 278
            ...|. ||....|..|.|.:..     .|...|.|.|:|..:|        .|.......|.|..
  Rat   181 LPFPE-PGYPAGPPLMSPHMGAHYRDCQGLGAPALDGYPLPTPDTSPLDGVEQDPAFFAAPLPGD 244

  Fly   279 VQLAAATLSAKYGFGSPLELSLPRLP-------------NAFPGLAHYPLDPTLALDLQARLQ-- 328
            ...|.|     |.:....:.::|..|             :|.||:    |.|..||.|.....
  Rat   245 CPAAGA-----YTYAQVSDYAVPAEPSAGPMRVGPDPSGSAMPGI----LAPPSALHLYYGAMGS 300

  Fly   329 -AMYAGSIYHPWRYLPLISPETPPSPP--------SSSGTGISSYGCVKSEKSSPNAVVASAASP 384
             |..||..:|.....|| .|:.||.||        .:.|.|..|        ..|.|:.....:.
  Rat   301 PAASAGRGFHAQPQQPL-QPQPPPPPPPPPPPQQHPTHGPGQPS--------PPPEALPCRDGTE 356

  Fly   385 PNIIXPTPL 393
            ||   ||.|
  Rat   357 PN--QPTEL 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	46/78 (59%)
Sox17	NP_001101372.1	HMG-box_SoxF_SOX17	62..142	CDD:438850	45/79 (57%)
		Sox17_18_mid	203..253	CDD:463454	12/54 (22%)