Protein Alignment Sox21a and tcf7l1b

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_571371.2
• Gene: tcf7l1b / 30556
• ZFINID: ZDB-GENE-991110-10
• Length: 550
• Species: Danio rerio
• Alignment Length: 505
• Identity: 100/505 - (19%)
• Similarity: 148/505 - (29%)
• Gaps: 225/505 - (44%)

  Fly     5 SALLHRSHSHSNGYTSSGSS--NHSHSSSLSPQLPGINLGLGMVGGLGMGMSVGVGSGSGNTTPP 67
            ||.|..|.|.|.|:.|:...  .|:|...|:|.:.                       ..|..||
Zfish   143 SAALKDSQSPSPGHLSNKVPVVQHAHMHPLTPLIT-----------------------YSNEFPP 184

  Fly    68 PMPPADLA---------VP----PAAPTP------------------VAPKMHQHTH-------- 93
            ..|||.|:         :|    ||..:|                  :.|:..||.:
Zfish   185 GTPPAHLSPEILDPKTGIPRTPHPAELSPYYPLSPGAVGQIPHPLGWLVPQQGQHMYPITAGGFR 249

  Fly    94 --------------------------HHGNSHHNAPTSH--------------------SNSNTG 112
                                      ||.:..|.....|                    :..:.|
Zfish   250 HPYPALAMNASMSSLVSSRFSPHLVPHHPHGLHQTGIPHPAIVSPVIKQEPNGELSPPVNTKSPG 314

  Fly   113 SHHNSHD---HIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEA 174
            .:....|   |||:|:||||::.:..|.|:..:.....::.|::.||..|..|:..::..:.:.|
Zfish   315 PNKKDEDKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELA 379

  Fly   175 KRLRALHMKEHPDY----KYRPRRKPKTLNKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSGPGS 235
            ::.|.||.:.:|.:    .|..|:|.|..||:.
Zfish   380 RKERQLHSQLYPGWSARDNYGKRKKRKRDNKTD-------------------------------- 412

  Fly   236 VGSPKDMQPQ-LSPLGQSLPH---------LHGHPHQSPYQSHPHHPHPHPHHVQLAAATLSAKY 290
             .:|:|...: ..|..|.||.         .||....||                   ||.||
Zfish   413 -STPEDFSMRSKKPCVQYLPQEKMIDSPGSSHGSMLDSP-------------------ATPSA-- 455

  Fly   291 GFGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPPSPPS 355
            ...||          |.|...|......|:|..:             |.|: ||:|   .|.|.|
Zfish   456 ALASP----------AAPAATHSEQAQPLSLTTK-------------PERF-PLLS---KPPPSS 493

  Fly   356 SSGTGISSYGCVKSEKSSPNAVVASAASPPNIIXPTPLRFGAGTSSSAEH 405
            ||.:..||.|               ..:||.:. |.|  |...|..|..|
Zfish   494 SSSSSSSSSG---------------LPTPPLLSRPLP--FALLTPPSPFH 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	20/74 (27%)
tcf7l1b	NP_571371.2	CTNNB1_binding	1..231	CDD:285538	23/110 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..76
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..326		2/27 (7%)
		SOX-TCF_HMG-box	325..396	CDD:238684	20/70 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910