Protein Alignment Sox21a and sox17

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_571362.2
• Gene: sox17 / 30544
• ZFINID: ZDB-GENE-991213-1
• Length: 413
• Species: Danio rerio
• Alignment Length: 383
• Identity: 103/383 - (26%)
• Similarity: 151/383 - (39%)
• Gaps: 121/383 - (31%)

  Fly    17 GYTSSGSSNHSHSSSLSPQLPGINLGLGMVGGLGMGMSVGVGSGSGNTTPPPMPPADLAVPPAAP 81
            ||:|...|..|..||:            |:.|:|.                 .|..|
Zfish     7 GYSSDDPSQTSSCSSV------------MMPGMGQ-----------------CPWVD-------- 34

  Fly    82 TPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKM 146
             |::|.....:.|.       ..|.:....|   .|...|:|||||||||::.:|:::||.||.:
Zfish    35 -PLSPLSDSKSKHE-------KCSAAGPGRG---KSEPRIRRPMNAFMVWAKDERKRLAQQNPDL 88

  Fly   147 HNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKP-----KTLNKS-PVP 205
            ||:|:||.||..||.|....||||::||:|||..||::||:|||||||:.     |.|..| |:|
Zfish    89 HNAELSKMLGKSWKALPMVDKRPFVEEAERLRVKHMQDHPNYKYRPRRRKQVKRNKRLEPSFPLP 153

  Fly   206 G----------GGGGGGGGGANGGVNAGGAGNSGPSGPGSVGSPKDMQ------------PQLSP 248
            |          .|...|..||                    |.|:..:            |..||
Zfish   154 GMCDAKMTLCTEGMSAGYSGA--------------------GLPQYCENHTLFESYSLPTPDPSP 198

  Fly   249 LGQSLPHLHGH-PHQSPYQSHPHHPHPHPHHVQLAAATLSAKYGFGSPLELSLPRLPN-AFPGL- 310
            :.......... ..||.:..|    |...||.|.....|:..:..|:...|...:..: |:..:
Zfish   199 MDAGTTEFFAQLQDQSAFSYH----HQQEHHFQEQTNILNDTHCHGNTQTLKSRQSHSIAYSNIN 259

  Fly   311 ------AHYPLDPTL-ALDLQARLQAMYAGS----IYHPWRYLPLISPETPPSPPSSS 357
                  .|.|::..| :::||   |..:..:    .:||..:|.:.:    .||.|||
Zfish   260 TNTNSNLHAPINAQLSSINLQ---QVFHENANPQISHHPGTHLNIFN----RSPSSSS 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	40/70 (57%)
sox17	NP_571362.2	SOX-TCF_HMG-box	62..133	CDD:238684	40/70 (57%)
		Sox_C_TAD	186..411	CDD:288887	28/136 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582387
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.970