DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox21a and Sox13

DIOPT Version :9

Sequence 1:	NP_001261827.1	Gene:	Sox21a / 39567	FlyBaseID:	FBgn0036411	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_006249824.1	Gene:	Sox13 / 289026	RGDID:	1309674	Length:	613	Species:	Rattus norvegicus

Alignment Length:	214	Identity:	73/214 - (34%)
Similarity:	101/214 - (47%)	Gaps:	38/214 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISALLHRSHSHSNGYTSSGSSNHSHSS------SLSPQLPGINLGLGMVGGLGMGMSVG------ 56
            :|.|.:.|.|.|....|.|....||.:      |..|.||        :|.||.|.:|.
  Rat   293 VSELPNTSSSPSLKMNSCGPRPSSHGAPTRDLQSSPPNLP--------LGFLGEGDAVTKAIQDA 349

  Fly    57 ---VGSGSGNTTPPPMPPADLAVPPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSN---TGSHH 115
               :.|.||.....|..|....:.....:|...::.::..|        |...:...   .||.|
  Rat   350 RQLLHSHSGALENSPSAPFRKDLISLDSSPAKERLEENCVH--------PLEEAMLGCDVDGSRH 406

  Fly   116 NSH----DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKR 176
            .|.    .||||||||||||::.:|||:.|..|.||||.|||.||:.||.:|..:|:|:.:|..|
  Rat   407 FSESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQAR 471

  Fly   177 LRALHMKEHPDYKYRPRRK 195
            |...|::::|||||:||.|
  Rat   472 LSRQHLEKYPDYKYKPRPK 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	39/70 (56%)
Sox13	XP_006249824.1	Herpes_UL46	<251..>419	CDD:355696	33/141 (23%)
Sox13	XP_006249824.1	SOX-TCF_HMG-box	415..486	CDD:238684	39/70 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342383
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740