Protein Alignment Sox21a and CFAP65

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: XP_011509205.1
• Gene: CFAP65 / 255101
• HGNCID: 25325
• Length: 1941
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 61/323 - (18%)
• Similarity: 93/323 - (28%)
• Gaps: 142/323 - (43%)

  Fly    99 HHNAP-------TSHSNSNTGSHHNSHDHIKRPMNAFMVW-----SRG-------------QRRK 138
            ||..|       |.||:|...:       |.:|.:  :.|     :||             :.:|
Human   549 HHQDPLFLDLMGTCHSDSTKPA-------ILKPQH--LTWYRTHLARGLTLYPPDILDAMLKEKK 604

  Fly   139 MAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRK-------- 195
            :|||.                    .|.....|.:.:.:.|      |.|.|.|...
Human   605 LAQDQ--------------------NGALMIPIQDLEDMPA------PQYPYIPPMTEFFFDGTS 643

  Fly   196 -----PKTLNKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSGPGSV------------------- 236
                 |..::..||.              |:.|..  .||..|..|
Human   644 DITIFPPPISVEPVE--------------VDFGAC--PGPEAPNPVPLCLMNHTKGKIMVVWTRR 692

  Fly   237 -GSPKDMQPQ---LSPLGQSLPHLHGHPHQSPYQSHPHHPHPH-PHHVQLAAATLSAKYGFGSPL 296
             ..|..:.|:   :.||......||..|           |||: .:.|:|.|..:.......|.:
Human   693 SDCPFWVTPESCDVPPLKSMAMRLHFQP-----------PHPNCLYTVELEAFAIYKVLQSYSNI 746

  Fly   297 ELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPP-SPPSSSG 358
            |             ....:.|:..|.::||..:.:||..:|    :|..|.:.|. .|..|||
Human   747 E-------------EDCTMCPSWCLTVRARGHSYFAGFEHH----IPQYSLDVPKLFPAVSSG 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	17/109 (16%)
CFAP65	XP_011509205.1	ASH	366..>432	CDD:464865