DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sox21a and Sox3

DIOPT Version :9

Sequence 1:NP_001261827.1 Gene:Sox21a / 39567 FlyBaseID:FBgn0036411 Length:407 Species:Drosophila melanogaster
Sequence 2:NP_033263.2 Gene:Sox3 / 20675 MGIID:98365 Length:450 Species:Mus musculus


Alignment Length:365 Identity:131/365 - (35%)
Similarity:161/365 - (44%) Gaps:106/365 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 NTTPPPMPPADLAVPPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSH--------- 118
            |...||.|.|...| ||||...           |.|..| |...:|:..|....::         
Mouse    86 NPVGPPTPAAGTGV-PAAPGAA-----------GKSGAN-PAGGANAGNGGSGGANGGGGGGGGG 137

  Fly   119 ----DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRA 179
                |.:|||||||||||||||||||.:|||||||||||||||:|||||:.:|||||||||||||
Mouse   138 GSDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRA 202

  Fly   180 LHMKEHPDYKYRPRRKPKTL---NKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSGPGSVGSPKD 241
            :||||:||||||||||.|||   :|..:|||....|...|.....|..|.:|    |..||...|
Mouse   203 VHMKEYPDYKYRPRRKTKTLLKKDKYSLPGGLLPPGAAAAAAAAAAAAAASS----PVGVGQRLD 263

  Fly   242 MQPQLSPLGQSLPHLHGHPHQSPYQSHPHHPHPHPHHVQLAAATLSAKYGFGSPLELSLPRLPNA 306
                      :..|::|..:.                   |.:.:..:.|:..|..:|.|..|.|
Mouse   264 ----------TYTHVNGWANG-------------------AYSLVQEQLGYAQPPSMSSPPPPPA 299

  Fly   307 FP--------GLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPPSPPSSSGTGISS 363
            .|        ||.:.|:.|..|........|..|.|.|             ....||::....::
Mouse   300 LPQMHRYDMAGLQYSPMMPPGAQSYMNAAAAAAAASGY-------------GGMAPSAAAAAAAA 351

  Fly   364 YG-----------------------CVKSEKSSPNAVVAS 380
            ||                       .||||.|||...:||
Mouse   352 YGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIAS 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sox21aNP_001261827.1 SOX-TCF_HMG-box 120..191 CDD:238684 60/70 (86%)
Sox3NP_033263.2 SOX-TCF_HMG-box 143..214 CDD:238684 60/70 (86%)
SOXp 213..306 CDD:289133 32/125 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167838559
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.840

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